Medication Description: Oxaphenamide (Oxaphenamidum)
Oxaphenamide (Oxaphenamidum). para-hydroxyphenylsalicylamide.
Synonyms: Auxobil, Drenamide, Dreol, Enidran, Neocol, Osalmid, Osalmidum, Salmidochol, etc.
White or white with a lilac-gray tint powder. Practically insoluble in water, easily in alcohol, alkaline solutions.
Strengthens the formation and secretion of bile, has an antispasmodic effect and relieves or reduces spasms of the biliary tract. It also has the ability to lower cholesterol in the blood, which is more clearly manifested in hypercholesterolemia.
Assign with chronic cholecystitis, cholangitis, cholecystohepatitis, cholelithiasis and other indications for the use of choleretic drugs. The drug can be used to enhance bile secretion before duodenal intubation.
Is ingested in tablets of 0.25 - 0.5 g 3 times a day before meals. The course of treatment is on average 15 to 20 days; if necessary, the drug is used for a longer time or repeated courses after a short break.
In acute inflammatory processes in the biliary tract and gallbladder, it is recommended to combine oxaphenamide with antibacterial drugs. In case of severe spasms and accompanying pains, it is advisable to administer cholinolytics, papaverine or other antispasmodic agents and promedol simultaneously with oxaphenamide.
Oksafenamid usually well tolerated and does not cause side effects. In some cases, with prolonged use there is a laxative effect.
Contraindications: acute inflammatory and pronounced dystrophic processes in the liver.
Form release: pills to 0.25 g.
Storage: in a well-closed container in a dark place.