Description of the medicine: Oxaphenamide (Oxaphenamidum)
OXAFENAMID (Oxaphenamidum). para-hydroxyphenyl salicylamide.
Synonyms: Auxobil, Drenamide, Dreol, Enidran, Neocol, Osalmid, Osalmidum, Salmidochol, etc.
Powder, white or white with a lilac gray shade. Almost insoluble in water, easily in alcohol, alkali solutions.
It enhances the formation and secretion of bile, has an antispasmodic effect and relieves or reduces biliary tract spasms. It also has the ability to lower blood cholesterol, which is more clearly manifested in hypercholesterolemia.
It is prescribed for chronic cholecystitis, cholangitis, cholecystohepatitis, gallstone disease and other indications for the use of choleretic drugs. The drug can be used to enhance bile secretion before duodenal sounding.
Take orally in tablets of 0.25 - 0.5 g 3 times a day before meals. The course of treatment is an average of 15 to 20 days; if necessary, the drug is used for a longer time or repeated courses are carried out after a short break.
In acute inflammatory processes in the biliary tract and gall bladder, it is recommended to combine oxaphenamide with antibacterial drugs. With severe spasms and the pain accompanying them, it is advisable to prescribe anticholinergics, papaverine or other antispasmodics and promedol along with oxaphenamide.
Oxafenamide is usually well tolerated and does not cause side effects. In some cases, with prolonged use, a laxative effect is observed.
Contraindications: acute inflammatory and severe dystrophic processes in the liver.
Release form: tablets on 0,25 g.
Storage: in a well-closed container in a dark place.