Description of the medicine: Nicodin (Nicodinum)
Pyridine-3-carboxylic (or nicotinic) acid hydroxymethylamide:
Synonyms: Bilamid, Bilizorin, Bilocid, Cholamid, Coloton, Felosan, Isochol, Nicoform, Nikoform, etc.
White crystalline powder. Soluble in water, difficult in alcohol.
Nicodine is a derivative of nicotinic acid amide and formaldehyde. It has a choleretic effect and, at the same time, has bacteriostatic and bactericidal properties, which is partially due to the elimination of the formaldehyde part of the drug molecule in the body. Another part of the molecule (nicotinamide) has the properties of vitamin PP and has a positive effect on liver function.
It is used for cholecystitis and hepatocholecystitis, as well as for urinary tract infections and gastroenteritis. Most effective for infections caused by E. coli. It is especially advisable to prescribe with a combination of inflammatory diseases of the biliary tract with gastritis and colitis. If necessary, take simultaneously with antibiotics. Nicodine does not have an antispasmodic and analgesic effect, therefore, with cramping and severe pain, the simultaneous use of antispasmodics and analgesics (promedol) is indicated.
Assign inside, 0.5 - 1, 0 g (1 - 2 tablets) 3-4 times a day before meals with 1/2 cup of water.
With diseases accompanied by febrile conditions, and with insufficient antibiotic effectiveness, the dose of nicodine is increased to 8 g per day; after lowering body temperature, the daily dose is reduced to 4 - 3 g, and then give 1, 0 - 0.5 g per day for 10 - 14 days. The course of treatment is repeated if necessary.
Nicodine is usually well tolerated. In some cases, with stagnant forms of hepatitis, intensification of pain is possible, and with anacid gastritis, intensification of dyspeptic phenomena is possible, to prevent them, it is recommended to take diluted hydrochloric acid, gastric juice or acidin-pepsin at the same time.
Release form: tablets of 0.5 g in a package of 10 pcs.,
Storage: in the dark place.