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Description of the medicine: Nicodinum (Nicodinum)
NICODINUM.
Pyridine-3-carboxylic acid (or nicotinic acid) oxymethylamide:
Synonyms: Bilamid, Bilizorin, Bilocid, Cholamid, Coloton, Felosan, Isochol, Nicoform, Nikoform and others.
White fine crystalline powder. It is soluble in water, it is difficult - in alcohol.
Nicodine is a nicotinic acid amide derivative and formaldehyde. Has a choleretic effect and at the same time has bacteriostatic and bactericidal properties, which is partly due to the elimination in the body of the formaldehyde part of the drug molecule. Another part of the molecule (nicotinamide) has the properties of vitamin PP and has a positive effect on liver function.
Applied with cholecystitis and hepatocholecystitis, as well as with infections of the urinary tract and gastroenteritis. The most effective for infections caused by E. coli. It is particularly advisable to appoint a combination of inflammatory diseases of the biliary tract with gastritis and colitis. If necessary, take simultaneously with antibiotics. Nicotine does not exert antispasmodic and analgesic effects, therefore, when spasms and severe pains are seen, simultaneous use of antispasmodics and analgesics (promedol) is indicated.
Assign inside, at 0.5 - 1, 0 g (1 - 2 tablets) 3 - 4 times a day before meals, drink 1/2 cup of water.
In diseases accompanied by febrile conditions, and with insufficient effectiveness of antibiotics, the dose of nicodine is increased to 8 g per day; After lowering body temperature, the daily dose is reduced to 4 - 3 g, and then give 1, 0 - 0.5 g per day for 10-14 days. The course of treatment, if necessary, is repeated.
Nicodinus is usually well tolerated. In some cases, with stagnant forms of hepatitis, pain can be increased, and with anacid gastritis, intensification of dyspeptic phenomena, simultaneous administration of diluted hydrochloric acid, gastric juice or acid-pepsin is recommended for their prevention.
Form release: a tablet of 0.5 grams in a package of 10 pieces,
Storage: in a place protected from light.
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