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Description medications: ziksorin (Zixorin)

Ziksorin (Zixorin). A 3-trifluoromethyl- ethyl-benzhydrol:

Colorless oily mass.

Synonyms: Flumetsinol, Flumecinol, Synklit.

The drug induces oxidase enzyme activity of liver microsomes; enhances the formation of glucuronides, promotes excretion of endogenous and exogenous metabolites, increases the secretion of bile. The drug acts on the microsomal enzymes relatively selectively expressed by other pharmacological effects has not. 3iksorin well absorbed when taken orally, is metabolized in the liver and the metabolites are excreted in urine and feces.

Apply with functional hyperbilirubinemia in patients with chronic diffuse diseases of the liver, jaundice, caused enzimopaty dobrakachestvennym and intrahepatic cholestasis, with food allergies, accompanied by jaundice, as well as for the prevention and treatment of neonatal jaundice.

There are performance ziksorin in the treatment of skin diseases (psoriasis, atopic dermatitis) and chemotherapy of TB patients.

Assign ziksorin adults (during or after meals) for chronic 0.4 - 0.6 g of (4 - 6 capsules) 1 time per week or 0.1 grams 3 times per day. The course of treatment 2 weeks. After 2 - 4 - week break possible repetition rate using the same dose or reduced, depending on the patient's condition.

When neonatal jaundice give the 2nd day of life to 10 mg / kg per day for 3 - 5 days. For the prevention of neonatal jaundice, pregnant provide for 1 - 3 days before the expected birth 0.4 g (4 capsules) once.

In atopic dermatitis in children ziksorin administered 2 mg / kg in 1 - 2 doses.

In applying the drug may nausea, idiosyncrasy.

Please note that due to liver enzyme induction (see. Phenobarbital) ziksorin can accelerate the metabolism at the same time used other drugs.

Product: capsules to 0.1 g flumetsinola in a package of 25 pieces.

Storage: in the dark spot.