Medication Description: Hyphotocin (Hyphotocinum)
Synonym: Pituitrin M.
Purified extract of the posterior lobe of the pituitary gland of cattle and pigs.
Colorless transparent liquid with low phenol odor (preservative); pH 3, 0 - 4, 0.
It has an oxytotic effect; mainly contains oxytocin, compared with pituitrin contains less vasopressin. Activity (<uterine>) is expressed in units of action (AU); 1 ml contains 5 U.
Used in obstetric and gynecological practice with weak labor, post-term pregnancy, hypotonic uterine bleeding, to normalize the involution of the uterus after childbirth and abortion.
In the first stage of labor, intramuscular injection of 0.2–0.4 ml (1–2 IU) is administered every 30 minutes (4–6 times a day); in the second period - up to 1 ml intramuscularly or intravenously in 500 ml of 5% glucose solution or slowly in 40 ml of 40% glucose solution.
For artificial stimulation of labor, gyphotocin is administered 2–4–6 hours after the opening of the membranes. The total amount of hyphotocine, introduced during childbirth or for artificial induction of labor, should not exceed 5 - 10 U.
Contraindications: discrepancy between the size of the pelvis and the head of the fetus, the presence of scars on the uterus, threatening uterine rupture, incorrect fetal position.
Product: in 1 ml ampoules (5 U).
Storage: List B. In a cool, dark place.