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Medication Description: Intermedinum

INTERMEDIN (Intermedinum).

Melanophore hormone median pituitary. Obtained from the pituitary gland of cattle and pigs.

White odorless amorphous powder and taste. Easily soluble in water and in isotonic sodium chloride solution.

Activity is determined biologically: 1 mg of the powder must contain at least 10 U.

Used to treat degenerative changes in the retina, hemeralopia, retinitis pigmentosa, myopic chorioretinitis.

The drug stimulates the activity of surviving cones and rods in the retina, improves adaptation to the dark, increases visual acuity.

Assign in the form of a 5% solution of 3 drops in the conjunctival sac of each eye (there is a gap of 5 minutes between the injections of each drop).

The duration of treatment is several months. Solutions prepare ex tempore.

There is evidence of the therapeutic efficacy of subconjunctival injection of intermedin. Dilute 0.04 - 0.05 g of intermedin in 1 ml of a 0.5% solution of novocaine; sterilized by boiling, injected under the conjunctiva at 0.2 - 0.3 ml 1 time in 3 days. For a course of 10 - 20 injections. Enter simultaneously in both eyes is not recommended.

For the introduction by electrophoresis, dissolve 0.02 g of intermedin in 25 ml of isotonic sodium chloride solution.

The active electrode - the anode - is placed on the eye; current + 2 mA, session duration 10 - 15 min. Sessions are carried out 2 times a week, only 10 sessions per eye.

Product: in hermetically sealed vials of 0.05 and 0.1 g with the application of ampoules containing respectively 1 or 2 ml of solvent (0.9% sodium chloride solution).

Storage: in a dark place at a temperature of + 15 to + 17 C.