Description of the medicine: Diethylstilbestrolum (Disethylstilboestrolum)
DIETHYLSTILBESTROL (Disethylstilboestrolum). trans-3, 4-Di- (para - hydroxyphenyl) - hexene-3.
Synonyms: Agostilben, Diethylstilbestrol, Diethylstilbestrolum, Estrobeme, Estromenin, Neoestranol, Newoestranol, Oestramon, Oestrogenin, Oestromenin, Oestrosyntal, Oroestron, Pabestrol, Stibbetrofil, Stilbestrofil, Stilbestrofil, Stilbestrofil, Stilbestrofil, Stilbestrofil, Stilbestrofil, Stilbestrofil, Stilbestrofil, Stilbestrofil
White crystalline powder. Soluble in alcohol, ether, fatty oils; very soluble in water.
A synthetic compound that has an estrogenic effect. It is superior to estrone and synestrol in terms of activity. 1 mg contains 20,000 units.
Previously, diethylstilbestrol was relatively widely used as an estrogenic agent in gynecological practice, as well as in hypertrophy and prostate cancer. Currently, due to side effects, it has limited use.
Diethylstilbestrol is sometimes used in the treatment of breast cancer in women. Like synestrol, it is prescribed only to women over 60 years of age. Doses of diethylstilbestrol due to its greater activity should be 2 to 3 times less than doses of synestrol.
Higher single and daily doses intramuscularly for malignant neoplasms 0.06 g.
Contraindications for use are the same as for estrone. The drug should not be prescribed for diseases of the liver and kidneys.
Treatment should be carried out under close medical supervision.
Release form: 3% solution in oil in ampoules of 1 ml (30 mg in 1 ampoule); used only in the treatment of patients with malignant neoplasms.
Storage: List B. In the dark place.