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Description medications: Testosterone propionate (Testosteroni propionas)

Testosterone propionate (Testosteroni propionas).

Adrosten-4-ol-17 b-3 -one propionate.

Synonyms: Agovirin, Androfort, Androlin, Andronate , Homosteron, Malestron, Oreton F, Perandren, Sterandryl, Synandrone, Testolutin, Testosterone propionate, Testosteronum propionicum, Testoviron, Virormone and others.

The white crystalline powder. Practically insoluble in water, easily soluble in alcohol, soluble in vegetable oils.

Testosterone is an endogenous male sex (adrogennym) hormone. It is produced in the male sex glands, is essential for the formation of the genital organs and the development of secondary sexual characteristics in men. Permanent testosterone production begins at puberty and continues until the waning of sexual function.

According to current data, in the body there are specialized androgen receptors. Circulating testosterone is converted in the blood in the organs - targets a 5 - a - digidrosteron (using 5- a -reductase enzyme) which binds to the androgen receptor and enters the cell nucleus. It is also possible in some tissues binding of testosterone to receptors.

For use in medical practice prepared synthetically testosterone propionate. He possesses biological and therapeutic properties of the natural hormone, but more slowly absorbed and more stable in the body than testosterone. Testosterone propionate is used parenterally; Orally it is inefficient (rapidly destroyed in the liver).

In addition to the specific action of androgen, testosterone, like all Androgens, has implications on other functions and systems of the body, in particular acts on nitrogen and phosphorus metabolism. It has anabolic effects and can be considered as an endogenous anabolic hormone. Lack of testosterone in the body (for lack of sexual development, after castration, and others.) Are usually accompanied by a breach of protein anabolism, atrophy of skeletal muscles and increasing deposits in the subcutaneous tissue and adipose tissue of internal organs. Substitution use of testosterone preparations can have with these changes the therapeutic effect. The anabolic effect of testosterone is also manifested in various pathological conditions involving enhanced dissolution of proteins (chronic infectious diseases, exhaustion, surgery, injuries, etc.) and disorders of calcium and phosphorus metabolism (osteoporosis).

Widespread use of testosterone as an anabolic agent prevents its strong androgenic effect.

Currently available drugs are similar in chemical structure to testosterone, but appears to be more selective anabolic effects.

Testosterone propionate is prescribed mainly for men with sexual underdevelopment, functional disorders in the reproductive system, klimakteicheskom syndrome, acromegaly.