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Description of the medicine: Testenatum (Testoenatum)

TESTENATE (Testoenatum).

A combined preparation containing a mixture of a solution in the oil of testosterone enanthate and testosterone propionate.

Similar preparations are released abroad under the name << Testosteron-Depot >>, etc. Testosterone enanthate (Testosteroni oenanthas) is an ether (enanthate) of androstene-4-ol-17 b -on-3.

Synonyms for testosterone enanthate: Androtardyl, Delatestryl, Orquisteron-E-Depot, Primoniat-Depot, Primotest-Depot, Primoteston-Depot, Proviron-Depot, Testathomen-Depot, Testo-Enant, Testoron-retard, Testoviron-Depot.

White or white with a slightly greenish or yellowish hue, the mass of the fine-crystalline structure with a weak odor. Very easily soluble in 95% alcohol and fat, slowly soluble in vegetable oils, almost insoluble in water. The melting point is +34 to +39 C.

As a weighted testosterone ester, testosterone enanthate has a slower and at the same time more prolonged action than testosterone propionate. The drug has a pronounced androgenic and anabolic effect. A single intramuscular injection of 10-20% of the testosterone solution of enanthate provides a hormonal effect within 3 to 4 weeks.

Testosterone enanthate can be used as a medication alone (intramuscularly as a 20% solution in oil at the rate of 0.1-0.2 g once every 2 to 4 weeks), but is mainly an integral part of the drug testanate for injection (Testoenatum pro Injectionibus).

A 10% testin for injections is available in 1 ml ampoules containing 111 mg (0.11 g) of testosterone enanthate and 24 mg (0.024 g) of testosterone propionate as a solution in peach oil. Transparent oily liquid of light yellow color.

The drug has the biological properties of testosterone. The combined use of two ethers (propionic and enanthic) provides a relatively rapid onset of the effect (due to a faster absorption of the first of them) and the duration of action (due to the prolonged action of the second). After a single intramuscular injection of testane, the therapeutic effect lasts 3 to 4 weeks. Along with a specific androgenic effect, testanate, like other androgenic drugs, stimulates the synthesis of protein in the body (anabolic effect).

Indications for the use of testane in men are the same as other androgenic and anabolic steroid drugs. In women, testanate is used for menopausal disorders (in the presence of contraindications to the use of estrogen preparations) and for breast and genital cancers (in combination with surgery or radiation therapy).

Enter the testate intramuscularly. Men with insufficient function of the sexual glands, hypogenitalism, eunuchoidism, after surgical removal of the genital glands, 0.1-1.2 g (1 ml of 10% or 20% solution) of testanate are prescribed once every 15 days; For a course of 10 to 15 injections.

When impotence due to functional deficiency of the gonads, as well as in men's menopausal syndrome, 0.1 g is administered once every 15 days; For a course of 5 injections.