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Description medications: methyltestosterone (Methyltestosteronum)

Methyltestosterone (Methyltestosteronum). A 17-methylandrosta-4-ol-17 b-3 -one.

Synonyms: Androral, Glosso-Sterandryl, Hormale , Madiol, Malogen, Metandren, Methyltestosterone, Oraviron, Oreton M, Stenendiol, Testoral, Virormoneoral

The white crystalline powder, odorless and tasteless. Easily soluble in alcohol, practically insoluble in water, slightly soluble in vegetable oils.

It is a synthetic analogue of testosterone. It has a biological and therapeutic properties of the natural hormone, and, like him, has a stimulating effect on the development of male reproductive organs and secondary sexual characteristics.

Methyltestosterone is not destroyed by enzymes of the gastrointestinal tract and retains activity upon ingestion. For best effect, it is recommended, however, not swallow a pill, a delay in its mouth (under the tongue) to complete resorption.

Methyltestosterone is a potent androgen, however, in comparison with testosterone propionate is less active; absorbed through the oral mucosa it is active in about 3 - 4 times lower than the testosterone propionate, introduced into the muscle.

In testimony to the intensive care male sex hormones is preferable to appoint an injection of testosterone propionate or testenata.

Methyltestosterone to men with delayed sexual development and sexual dysfunction, with climacteric syndrome.

In primary and eunuchoidism gipogenitalizme motivated congenital underdevelopment sexual glands or surgical removal of their appoint 0.02 - 0.03 grams of the drug (sometimes more) a day.

At moderate forms gipogenitalizme sufficient dose of 0.02 - 0.025 g (20 - 25 mg) daily or every other day. Treatment is carried out over a long time depending on the severity of the disease and treatment. For the treatment of impotence due to functional deficiency sex glands, fatigue and nervous exhaustion appoint 0,01 - 0,02 g per day. When taken orally menopause syndrome 0,005 - 0,015 g for 1 - 2 months, with prostate cancer in the early stages - 0.02 - 0.03 g per day over 1 - 2 months; treatment is repeated depending on the current process. Patients with prostate cancer methyltestosterone contraindicated.

When delay puberty, infantilism and growth retardation in children (boys) and adolescents methyltestosterone administered 0,005 - 0,01 g (5 - 10 mg) per day; the duration of treatment depends on the resulting effect.

Sometimes methyltestosterone administered (0,005 - 0,015 grams per day) as a tonic (partly due to the anabolic effect) rekonvalestsentam after acute infection, trauma, surgery, with early senile withering, etc. For this purpose, however, it is better to use anabolic steroids (cm.).

Methyltestosterone sometimes used in the treatment of angina. Doses individualize assigning of 0.01 - 0.02 g 1 times a week up to 0.01 g every day or two.