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Description of the medicine: Methandrostenolone (Methan drostenolonum)

METHANDROSTENOLONE (Methan drostenolonum). 17 a-Methylandrostadien-1, 4-ol-17 b -one 3.

Synonyms: Dianabol, Nerobol, Anabolex, Anabolin, Anaboral, Bionabol, Danabol, Dehydromethyltestosteron, Dianabol, Distranorm, Lanabolin, Metanabol, Metandienone, Metandienonum, Metastenol, Methastenon, Nabolin, Nerobol, Novabol, Perabol, Perabol, Perabol

Crystalline powder, white or white with a yellowish tint. Very slightly soluble in water, slightly soluble in alcohol.

The chemical structure and biological effect is close to testosterone and its analogues. It has androgenic activity, however, in this respect is much less active than testosterone, however, it has a pronounced anabolic effect (see Testosterone propionate). The androgenic effect of methandrostenolone is 100 times less than the similar effect of testosterone propionate with approximately the same anabolic activity.

The main indications for the use of methandrostenolone, as well as other anabolic steroids, are violations of protein anabolism during cachexia of various origins, asthenia, infectious and other diseases accompanied by protein loss. The drug is prescribed to convalescents after severe injuries, operations, burns.

In endocrinological practice, methandrostenolone and other anabolic steroids are used for interstitial pituitary insufficiency, chronic adrenal insufficiency, toxic goiter, diabetic angiopathies (retinopathy and nephropathy), steroid diabetes, pituitary dwarfism.

In therapeutic practice, it is prescribed for chronic coronary insufficiency and myocardial infarction, myocarditis, rheumatic heart disease and atherosclerotic cardiosclerosis, myocardial overstrain, gastric ulcer and duodenal ulcer, chronic kidney ulcer disease, accompanied by chronic protein loss and azotemia.

These drugs are also used for osteoporosis, delayed formation of bone callus, large fractures and after plastic surgery on bones, with myopathies and progressive muscular dystrophy; amyotrophic lateral sclerosis; progressive myopia and senile degeneration of the retina, eczema, psoriasis.

In pediatric practice, it is used for stunting, anorexia, nutritional decline, etc.

Anabolic steroids are sometimes recommended for elderly and senile people to improve compensatory and adaptive processes.

Methandrostenolone is taken orally. Doses and duration of treatment are set individually depending on the nature of the disease, the age of the patient, the effectiveness and tolerability of the drug, the results of clinical and biochemical studies. Typically, the daily dose for adults is 0.005-0.01 g (1 tablet of 5 mg 1 to 2 times a day before meals). In the first days of treatment, the daily dose can be increased to 0.02 g (4 tablets), and in some cases (with exhaustion, cachexia, uremia) - up to 0.03 g (30 mg). For long-term therapy, 0.005 g (5 mg) per day is prescribed.