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Description of the drug: Methylandrostendiol (Methylandrostendiolum)

METHYLANDROSTENDIOL (Methylandrostendiolum). 17 a-Methylandrostene-5-diol-3 b, 17.

Synonyms: Anadiol, Androdiol, Anormon, Diandrin, Diolostene, Masdiol, Mestendiol, Metandiol, Metandriol, Metasteron, Methandriol, Methandriolum, Methostan, Neosteron, Notandron, Novandrol, Protandren, Stenediol, Stenosterone, Testodiol, Tonormon, Troformone.

White crystalline powder odorless. Almost nerastvorim in water, soluble in alcohol.

The chemical structure and biological properties are close to methyltestosterone, but it has lesser androgenic activity with a relatively higher anabolic effect. In this regard, it can be used in disorders of protein metabolism, with a relatively weak androgenic (masculinizing) effect.

They are used to strengthen protein anabolism, in convalescent patients after severe injuries, surgeries, infectious and other diseases, with osteoporosis, growth retardation, exhaustion, etc.

The drug can be prescribed as an anabolic agent for women, but due to greater androgenic activity compared to other anabolic steroids (methandrostenolone, etc.), treatment should be performed under the supervision of a gynecologist.

Take sublingually. Adults appoint 0,025 - 0,05 g per day; Children and patients with growth retardation - at the rate of 1, 0 - 1, 5 mg / kg, but not more than 0.05 g (50 mg) per day. At the same time, food is prescribed, rich in proteins. The course of treatment 4 weeks; Breaks between courses 2 - 4 weeks.

Higher doses for adults: single 0.025 g, daily 0.1 g.

With menopausal disorders and dysmenorrhea appoint 0,025 - 0,05 g per day. With breast cancer, the dose is increased to 0.2-0.3 g per day with a gradual decrease to 0.1-0.075 g per day.

When using methylandrostenediol, there are side effects: violations of the liver with an increase in its size and jaundice, allergic reactions, in women - the phenomenon of virilization.

The drug is contraindicated in prostate cancer, acute liver disease. Relative contraindications: pregnancy, lactation, decompensation of carbohydrate metabolism and acidosis in diabetes mellitus.

Form release: tablets under the tongue of 0.01 and 0.025 grams (10 and 25 mg).

Storage: List B. In the dark place.