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Medication Description: Methylandrostendiol (Methylandrostendiolum)

METHYLANDROSTENDIOL (Methylandrostendiolum). 17 a -Methylandrosten-5-diol-3 b, 17.

Synonyms: Anadiol, Androdiol, Anormon, Diandrin, Diolostene, Masdiol, Mestendiol, Metandiol, Metandriol, Metasteron, Methandriol, Methandriolum, Methostan, Neosteron, Notandron, Novandrol, Protandren, Stenediol, tester, tester, tester, tester, tester, tester, tester, tester, tester, tester, tester, tester, tester, testera, detondron, Novoron, Anormon

White crystalline powder; odorless. Practically insoluble in water, soluble in alcohol.

In terms of chemical structure and biological properties, it is close to methyltestosterone, however, it has less androgenic activity with a relatively higher anabolic effect. In this regard, it can be used in disorders of protein metabolism, providing a relatively weak androgenic (masculinizing) effect.

Used to enhance protein anabolism, in convalescents after serious injuries, operations, infectious and other diseases, osteoporosis, growth retardation, exhaustion, etc.

The drug can be prescribed as an anabolic agent for women, but because of the greater androgenic activity compared with other anabolic steroids (methandrostenolone, etc.), treatment should be carried out under the supervision of a gynecologist.

Accept sublingually. Adults appoint 0.025 - 0.05 g per day; children and patients with growth retardation - at the rate of 1, 0 - 1, 5 mg / kg, but not more than 0.05 g (50 mg) per day. At the same time prescribed food rich in proteins. The course of treatment is 4 weeks; breaks between courses 2 - 4 weeks.

Higher doses for adults: single 0.025 g, daily 0.1 g.

In menopausal disorders and dysmenorrhea, 0.025-0.05 g daily is prescribed. In breast cancer, the dose is increased to 0.2–0.3 g per day, with its gradual decrease to 0.1–0.075 g per day.

With the use of methylandrostediol possible side effects: liver dysfunction with an increase in its size and jaundice, allergic reactions, in women - the phenomenon of virilization.

The drug is contraindicated in prostate cancer, acute liver disease. Relative contraindications: pregnancy, lactation, decompensation of carbohydrate metabolism and acidosis in diabetes mellitus.

Product form: tablets under the tongue at 0.01 and 0.025 g (10 and 25 mg).

Storage: List B. In the dark spot.