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Description of the medicine: Ascorbic acid (Acidum ascorbinicum)

Ascorbic Acid (Acidum ascorbinicum).

VITAMIN C (Vitaminum C). g-Lactone 2, 3-dehydro-L-gulonic acid.

Synonyms: Acidum ascorbicum, Ascorbin, Ascorbit, Ascorvit, Cantan, Cantaxin, Cebione, Cecon, Celin, Ceneton, Cevalin, Cevex, Laroscorbine, Redoxon, Scorbumine, Vicin, Vitascorbol, etc.

White crystalline powder of sour taste. Easily soluble in water (1: 3, 5), soluble in alcohol. Solutions for injection are prepared with the addition of sodium bicarbonate and stabilizers; sterilized at + 100 ° C for 15 minutes; pH of solutions 6, 0 - 7, 0.

Ascorbic acid (vitamin C) is found in significant quantities in products of plant origin (rose hips, cabbage, lemons, oranges, horseradish, fruits, berries, needles, etc.). Small amounts of vitamin C are found in animal products (liver, brain, muscles). For medical purposes, ascorbic acid is obtained synthetically.

Ascorbic acid plays an important role in the life of the body. Due to the presence of a dienol group in the molecule (- СОН = СОН -), it has strongly expressed reducing properties. Participates in the regulation of redox processes of carbohydrate metabolism, blood coagulation, tissue regeneration, and the formation of steroid hormones. One of the important physiological functions of ascorbic acid is its participation in the synthesis of collagen and procollagen and the normalization of capillary permeability.

The human body is not able to synthesize vitamin C; the need for it is satisfied by the vitamin introduced with food. Lack or absence of it leads to the development of hypo - or vitamin deficiency (scurvy).

The daily requirement for ascorbic acid for an adult is about 70-100 mg; for children aged 6 months to 1 year - 20 mg; from 1 year to 1, 5 years - 35 mg; from 1, 5 to 2 years, 40 mg; from 3 to 4 years - 45 mg; from 5 to 10 years - 50 mg; from 11 to 13 years - 60 mg; for boys 14-17 years old - 80 mg; for girls 14 to 17 years old - 70 mg.

Crystalline ascorbic acid and preparations containing it are used for prophylactic and therapeutic purposes in all cases when the body needs additional administration of this vitamin: for the prevention and treatment of scurvy, with hemorrhagic diathesis, nose, lung, liver, uterine and other bleeding; including those caused by radiation sickness, as well as an overdose of anticoagulants, with infectious diseases and intoxications, liver diseases, pregnant nephropathy, Addison’s disease, sluggishly healing wounds and bone fractures, dystrophies and other pathological processes. The drug is also prescribed for increased physical labor, mental stress, during pregnancy and lactation.

There is evidence of a positive effect of ascorbic acid on lipid metabolism in atherosclerosis.

Ascorbic acid is prescribed orally (after eating), intramuscularly or intravenously.