Description of the medicine: Lipoic acid (Acidum lipoicum)
LIPOIC ACID (Acidum lipoicum). 6, 8-Dithiooctanoic acid.
Synonyms: Acidum thiocticum, Biletan, Heparlipon, Protogen, Thioctacid, Thioctan, Tioctacid, Tioctan, etc.
The crystalline powder is light yellow in color, with a bitter taste, with a specific odor. Practically insoluble in water, easily soluble in alcohol. The lipoic acid sodium salt is highly soluble in water.
Lipoic acid is a coenzyme involved in the oxidative decarboxylation of pyruvic acid and a-keto acids, and plays an important role in the process of energy formation in the body. By the nature of the biochemical action, lipoic acid approaches the vitamins of group B.
Lipoic acid is involved in the regulation of lipid and carbohydrate metabolism, has a lipotropic effect, affects cholesterol metabolism, improves liver function, has a detoxifying effect in case of poisoning with heavy metal salts and other intoxications.
In the body is in different organs, especially a lot of it in the liver, kidneys, heart. For use as a medicine, it is obtained synthetically.
Used for prophylactic and therapeutic purposes in the complex treatment of coronary atherosclerosis, liver diseases (Botkin’s disease - mild and moderate course, chronic hepatitis, cirrhosis), diabetic polyneuritis, intoxication. There is evidence of the use of lipoic acid (in combination with other agents) in the treatment of acne patients.
It is taken orally in the form of tablets after meals at 0.025-0.05 g 2 to 3 times a day. Intramuscularly injected in 2 - 4 ml of 0.5% solution (0.01 - 0.02 g) per day. The average duration of treatment is 20 - 30 days. If necessary, the treatment is repeated after a break lasting 1 month.
Children under the age of 7 years are prescribed inside at 0.012 g, over 7 years old - at 0.012-0.024 g 2 to 3 times a day.
When taking the drug, dyspeptic symptoms (pain in the epigastric region, heartburn), allergic skin rashes are possible. Caution should be exercised when prescribing the drug to patients with hyperacid gastritis and gastric ulcer, as well as with a tendency to allergic reactions.
Method of release: powder; coated tablets of 0.012 and 0.025 g; 0.5% solution in ampoules of 2 ml.
Storage: in a cool, dark place.
Rp.: Tab. Ace. lipoici 0,025 N. 50
DS 1 tablet 3 times a day
Rp.: Sol. Ace. lipoici 0.5% 2 ml
DtdN 10 in ampull.
S. 2 ml 2 times a day intramuscularly
Lipoic acid is part of the complex (multivitamin) drug Complivit.