Description of the medicine: Reogluman (Rheoglumanum)

REOHLUMAN (Rheoglumanum).

The drug, which is a 10% solution of dextran with a molecular weight of 40,000 # 10,000 with the addition of 5% mannitol and 0.9% sodium chloride in water for injection.

Clear, colorless, odorless liquid; PH 4, 0-6, 5; The relative viscosity at a temperature of + 25 ° C is not more than 7, 0.

The drug is considered as a polyfunctional blood substitute: reduces the viscosity of the blood, helps restore blood flow in small capillaries, reduces the aggregation of blood cells, has a detoxification, osmodirtic, and hemodynamic effects.

Apply rheogluman to improve capillary blood flow in diseases accompanied by a violation of microcirculation and fluid retention in the body, including traumatic, surgical, cardiogenic, burn shock, in violation of arterial and venous blood flow (thrombosis, thrombophlebitis, endarteritis, etc.), for detoxification With burns, peritonitis, pancreatitis, etc.

Introduce reogluman intravenously, drip. Begin with the introduction of 5 - 10 drops per minute for 10 - 15 minutes. After the administration of 5 to 10 drops, and then 30 drops, take breaks for 2 to 3 minutes; If there are no undesirable reactions, go to the introduction of the drug at a rate of 40 drops per minute.

Doses and the speed of administration are selected individually depending on the indications, the patient's condition, diuresis.

To maintain the electrolyte balance, it is advisable to administer solutions containing potassium and sodium simultaneously with the reogluman. In the complex therapy of shock, usually from 400 to 800 ml of reogluman are administered for 30-60 minutes (under the control of hemodynamic and diuresis parameters).

In cardiovascular surgery, 30 to 60 minutes before the operation, 10 ml / kg of reogluman is administered, during operation 400 to 500 ml and every day after the operation for 5 to 6 days, drip at a rate of 10 ml / kg.

In acute renal and hepatic insufficiency (with a preserved filtration capacity), 400-800 ml are administered once; Then daily (for 3 - 5 days) is used at the rate of 10 ml / kg for administration, under the control of the water-electrolyte and acid-base state and the blood coagulation system.

Possible complications, precautions and contraindications are the same as when using polyglucin. Do not use reogluman for excessive hemodilution (hematocrit below 25 units) and with hemorrhagic diathesis (thrombocytopenia).

Product: in bottles of 100; 200 and 400 ml.

Storage: at a temperature not lower than +10 and not higher than + 25 C. During transportation, a short-term storage temperature decrease of up to -10 ° C is possible.