Description of the medicine: Sodium hydrogen carbonate (Natrii hydrocarbonas)

SODIUM HYDROCARBONATE (Natrii hydrocarbonas).

Synonyms: Sodium bicarbonate, Sodium bicarbonate, Soda bicarbonate, Natrium bicarbonicum, Natrium hydrocarbonicum, Sodium bicarbonate.

White crystalline powder without a smell, salty-alkaline taste. Soluble in water (1: 2) with the formation of alkaline solutions (pH 5% solution 8, 1), virtually nerastvorim in alcohol. The aqueous solutions are sterilized at a temperature of + 120 ° C for 12 minutes (in hermetically sealed bottles with the addition of stabilizers).

Applied with various diseases accompanied by severe acidosis (diabetes mellitus, infections, etc.), to combat acidosis during surgical interventions, etc.

Widely used sodium hydrogencarbonate (as well as other alkalis) has both an antacid agent with increased acidity of gastric juice, peptic ulcer of the stomach and duodenum.

Sometimes sodium hydrogencarbonate is used in the form of drip intravenous infusions or rectal suppositories in hypertensive disease, symptomatic renal hypertension and chronic renal failure. The effect is associated with an increase in the release of sodium and chlorine ions and an increase in osmotic diuresis. It is noted that against the background of the introduction of sodium bicarbonate, the effect of antihypertensive drugs (preparations of rauwolfia, etc.) is enhanced.

Sodium bicarbonate also facilitates the phenomena of "motion sickness" (sea and air sickness).

Due to the fact that the increase in alkaline blood reserves caused by the drug shifts the reaction of bronchial mucus to the alkaline side and makes sputum less viscous, it is used as an expectorant.

Locally (in the form of rinses, rinses), sodium bicarbonate solutions are prescribed for inflammatory diseases of the eyes, mucous membranes of the upper respiratory tract, etc., as well as for contact with mucous membranes and skin acids.

Apply sodium bicarbonate inside, intravenously, in candles, for enemas and topically (in the form of solutions).

When ingested, the drug quickly neutralizes the hydrochloric acid of gastric juice and has a pronounced antacid effect. It must be taken into account, however, that when hydrochloric acid is neutralized with sodium hydrogencarbonate, carbonic acid is released which exerts an excitatory effect on the receptors of the gastric mucosa, increases the release of gastrin and may cause a secondary increase in secretion. In addition, when using large doses, an excess of antacid can be absorbed into the blood and cause disturbances in the acid-base state.

Often, sodium hydrogencarbonate is prescribed together with holinoliticheskimi means (see Tablets "Bicarbon"), enveloping, adsorbing and other substances (see Tablets "Vikair", Tablets "Vikalin", etc.), while their therapeutic effectiveness increases, side effects decrease .

Recently, the main use as antiulcer drugs were preparations of new groups (see.