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Salicylates


- A group of drugs derived from salicylic acid by replacing hydrogen therein different radicals. The first was introduced in the treatment of sodium salicylate (1875-1876 years) as an antipyretic, and antirheumatic agent. In the application of salicylates may experience side effects: tinnitus, hearing loss, heavy perspiration, swelling and so on. There hypersensitivity in asthma - increased heart attack and gain, allergic reactions (skin rash), ingestion - the phenomenon of gastritis (heartburn, nausea, pain in the stomach, vomiting). Salicylates cause a decrease in blood prothrombin, which can promote bleeding.
In modern therapy salicylates have a very large spread. World production of several thousand tonnes per year.