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Hypnotics (barbiturates)


All derivatives of barbituric acid (phenobarbital, barbital, medal, etaminal-patria, a mixture of Sereysky, tardil, bellaspop, bromital, etc.) are absorbed quite quickly and almost completely in the gastrointestinal tract. Lethal dose: about 10 medical doses with large individual differences. Acute sleeping pills poisoning is primarily accompanied by inhibition of the functions of the central nervous system. The leading symptom is respiratory failure and the progressive development of oxygen starvation. Breathing becomes rare, intermittent. All types of reflex activity are suppressed. Pupils initially narrow and respond to light, and then (due to oxygen starvation) expand and no longer respond to light. Renal function sharply suffers: a decrease in diuresis contributes to the slow release of barbiturates from the body. Death occurs as a result of paralysis of the respiratory center and acute circulatory disorders.