hyperprolactinemia
Hyperprolactinemia - galactorrhea-amenorrhea syndrome in women and hypogonadism in men. It occurs when increasing the secretion of prolactin by the pituitary gland.
Etiology and pathogenesis. Pituitary tumors (micro and macroadenoma), violation of prolactin secretion due to the use of drugs that block the action of dopamine (neuroleptics, Reglan, and others.), Contraceptives (estrogen); long untreated primary hypothyroidism. Elevated levels of prolactin reduces secretion of gonadotropins occurs infertility.
Symptoms within. In women, galactorrhea may be spontaneous or determined when pressed. Observed or amenorrhea, or opsomenoreya or absence of ovulation; decreased libido, uterine hypoplasia, vagina, obesity varying degrees. The men - or oligo-azoospermia, impotence, decreased libido, seldom-gynecomastia. Significant violations occur in individuals who become ill in adolescence.
Diagnosis. Pituitary tumor is detected on the side kraniogramme or computed tomography. Characterized by an increase in prolactin levels, reduction of LH, FSH, estrogen in women, testosterone in men. In all cases of infertility and menstrual disorders it is recommended to define the level of prolactin in the blood plasma.
Treatment. When macroprolactinoma surgery is used when mikroprolaktinomah parlodel prescribed at a dose of 2.5-10 mg / day for a long time.
- Endocrine and metabolic diseases
- Acromegaly
- virilnoe syndrome
- Congenital disorders of sexual differentiation
- hunger disease
- hyperparathyroidism
- Hypogonadism (male)
- Hypoparathyroidism (tetany)
- Hypothyroidism (myxedema)
- Pituitary dwarfism (dwarfism)
- Diabetes insipidus
- diabetes diabetes
- dispituitarism youth
- Goiter Graves
- Goiter endemic
- Pituitary basophilia
- Interstitial-pituitary insufficiency
- adrenal insufficiency
- Obesity
- Tumors
- Advanced sexual development
- thyroiditis
- pheochromocytoma
- Endocrine ophthalmopathy
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