Adrenogenital syndrome
Adrenogenital syndrome is characterized by hyperfunction of the adrenal cortex and an increased content of androgens in the body, which causes the phenomenon of virilization. There are congenital and post-pubertal syndromes. Congenital syndrome is a hereditary disease caused by a defect in the enzyme system of 21-hydroxylase or a tumor of the adrenal cortex.
Symptoms, course. With the congenital form of the syndrome, the effect of androgens begins during the period of intrauterine development, at birth it is manifested by the appearance of the urogenital sinus and clitoral hypertrophy. The period of puberty in these children begins early (at 6-7 years) and proceeds through a heterosexual type (male secondary sexual characteristics, absence of mammary glands and menstrual function). Postpubertate form is characterized by hirsutism, oligomenorrhea or amenorrhea, often infertility, atrophy of the mammary glands, a decrease in the size of the uterus and ovaries, mild hypertrophy of the clitoris, i.e., signs of the viral syndrome (see Endocrine and metabolic diseases).
Drugs of glucocorticoid hormones (cortisone, prednisolone, dexamethasone). Dosage depends on the age and severity of the syndrome. The introduction of these drugs normalizes the synthesis of hormones by the adrenal cortex and the function of the hypatalamus-pituitary-ovary system (the appearance of secondary sexual characteristics by the female type, the restoration of the menstrual cycle). With a congenital adrenogenital syndrome, the clitoris is amputated and the artificial entrance to the vagina is formed.
Algodismenorea-painful menstruation. It arises as a result of infantilism, incorrect position of the uterus (hyperanteflexia, retroversion), inflammatory processes in the genitals, endometriosis and other diseases, as well as increased excitability of the central nervous system. It is usually observed in young women (often with infertility). Pain appears several days before menstruation, it is often very strong, which sometimes makes the sick disabled. Pain syndrome is accompanied by a variety of autonomic disorders (headache, nausea, vomiting, dizziness, etc.). The pain stops with the onset of menstruation.
Treatment should be aimed at eliminating the causes that cause pain. With functional algodismorrhea, general restorative treatment with antispasmodics (no-shpa, papaverine, belladonna, atropine) has been shown. As an anesthetic, amidopyrine and analgin are used. Tranquilizers are shown: meprotan (meprobamate), trioxazine, diazepam (seduxen). When inflammatory processes in the small pelvis are carried out physiotherapy treatment; Abdominal-sacral diathermy, mud cure, etc. From hormonal drugs prescribe progesterone, which reduces the excitability of the uterus, 5-10 mg for 8 days before menstruation in / m. Taking into account the increase in the activity of endogenous prostaglandins, prescribe drugs that inhibit their activity (for example, candles with naprosin at 500 mg 1-2 times a day). Endometriosis is treated conservatively or promptly (see Endometriosis).
- Female diseases
- Amenorrhea
- Anovulatory cycle
- Ovarian apoplexy
- Bartholinitis
- Beli
- Infertility
- Vaginitis (colpitis)
- Vulvit
- Vulvovaginitis
- Gonorrhea
- Itching of the vulva
- Ovarian cyst
- Ovarian cyst
- Claurosis of the vulva
- Menopause. Climacteric neurosis
- Bleeding uterine dysfunctional
- Leukoplakia vulva, cervix
- Myoma of the uterus
- Myoma of the uterus
- Oophoritis
- Omission and prolapse of the uterus
- Parametritis
- Polyps of the cervix and the body of the uterus
- Premenstrual syndrome
- Salpingitis
- Syndrome of sclerocystic ovaries
- Tuberculosis of female genital organs
- Endometriosis
- Endometritis
- Endocervicitis
- Erosion (dysplasia of the mucous membrane) of the cervix
Comments
Commenting on, remember that the content and tone of your message can hurt the feelings of real people, show respect and tolerance to your interlocutors even if you do not share their opinion, your behavior in the conditions of freedom of expression and anonymity provided by the Internet, changes Not only virtual, but also the real world. All comments are hidden from the index, spam is controlled.