sclerocystic Ovary Syndrome

Sclerocystic ovary syndrome (Stein -Leventalya syndrome) usually occurs in disorders of the hypothalamic-gipofiearnoy system dysfunction of the adrenal cortex or primary ovarian lesions (violation of the biosynthesis of steroid hormones) and is characterized by amenorrhea of different duration (sometimes acyclic bleeding), and other manifestations of hirsutism virilnogo syndrome (see chap. "Endocrine and metabolic diseases"), obesity, infertility and the presence of enlarged polycystic-ovary. Usually occurs at age 20-30 years.

Diagnosis is based on the typical complaints of the patient and detects when gynecological examination bilateral ovarian enlargement. The diagnosis specify when X-rays of the pelvic organs with the help of pneumoperitoneum, ultrasound and laparoscopy. When hormonal studies establish several high content of 17-keto steroids (up to 20 mg / day) and androstenediol. functional diagnostics tests indicate anovulation. To exclude the syndrome adrenal genesis sample using dexamethasone (1 mg 2 times a day for 3-5 days), which show a decrease in the concentration of 17-keto steroids in the urine., / P>

Treatment. More often resorted to ovarian wedge resection. The operation was carried out after uterine curettage (removal of pathologically altered endometrium). Attempts were made to the treatment of drugs that stimulate ovulation (clomiphene).

Prognosis is usually favorable - the restoration of the normal menstrual cycle after surgery in 50-60% of patients; pregnancy occurs rarely.