Vitamin P
Vitamin R. A number of substances - flavonoids, possessing the ability (especially in combination with ascorbic acid) to reduce permeability and fragility of capillaries, to participate in oxidation-reduction processes and to inhibit the action of hyaluronidase belong to the vitamin P group.
Flavonoids possess both antioxidant properties , protect against oxidation of ascorbic acid and adrenaline, are contained in the form of glycosides in many plants, especially in hips, lemons and other citrus fruits, black currant berries, ordinary and blackberry berries, walnuts, green leaves, etc. -vitamin activity has been sufficiently studied in flavonones (hesperidin, eriodictin), flavonols (rutin, quercetin, etc.), chalcones (hesperidin-methyl-chalcon), catechins (I-epicatechin, I-epigalocatechin, etc.), coumarins (esculin) , Gallic acid, etc.
Vitamin P preparations are used for the prevention and treatment of hypo-and avitaminosis P and in diseases accompanied by impaired vascular permeability, hemorrhagic diathesis, hemorrhages in the retina, capillarotoxicosis, radiation sickness, septic endocarditis, glomerulonephritis, hypertension, rheumatism, arachnoiditis, allergic Diseases, measles, scarlet fever, typhus, thrombopenic purpura, etc., as well as for the prevention and treatment of capillary lesions associated with the use of anticoagulants (dicumarin, phenylin and their analogues), salicylates, arsenic compounds. Prescribe drugs of vitamin P concomitantly with ascorbic acid.
Rutin is found in the leaves of rue fragrant and other plants. For medical use is extracted from the green mass of buckwheat and from buds of Sophora flowers of Japanese. Rutin is a greenish-yellow fine-crystalline powder without taste and smell, insoluble in water, soluble in dilute solutions of caustic alkalis. Assign adults 2-3 times a day for 0,02-0,05 g.
Ascorutin - tablets containing rutin and ascorbic acid (by 0,05).
Urutin is a solution with 0.025 grams of rutin and 0.05 g of urotropin, a dark yellow liquid that is odorless, neutral, applied subcutaneously or intramuscularly as a soluble rutin preparation (discontinued).
Quercetin - a yellow crystalline powder, odorless and tasteless, insoluble in water, soluble in alkali solutions, is prescribed 0,02 g 5 times a day for 5-6 weeks. Vitamin P from leaves of a bush of a tea plant - amorphous greenish-yellow, bitter-astringent powder, soluble in water and alcohol. Assign in powders or tablets of 0.05 g in pure form and with ascorbic acid 2-3 times a day.
Caution should be exercised in appointing patients with impaired thyroid function. Vitamin P from citrus - amorphous light yellow powder, insoluble in water, soluble in alkaline solutions. Assign in powders and tablets of 0.05-0.1 g 2-3 times a day in pure form and with ascorbic acid. Vitamin R from chokeberry aronia - a dark powder with odor and taste of aronia, insoluble in water. Contains hesperidin, rutin, quercetin, etc. The dose is 0.05 g, the prescriptions are the same. Preparations of vitamin P should be administered with caution in cases of increased blood clotting.
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