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Interchangeable drugs and medicines (tables, annotation, prohibited)




  • Interchangeable drugs and medicines
  • Annotated to unauthorized substitution of more expensive drugs for their cheaper counterparts
  • Prohibited, fraudulent and useless drugs and their manufacturers





  • Interchangeable drugs and medicines


    Many readers hooked phrase about the unauthorized replacement of more expensive drugs for their cheaper counterparts on the advice of "Spare the patients with a difficult financial situation" pervostolnikov. Well, there is a saying ... Sorry ... left the wolf mare's tail and mane ... cries .... that's supposedly evil doctor to prescribe anger insanely expensive treatment when it was possible to manage and less expensive ... begin to exert more so to the best of a small clarification.

    In your life there is no more necessary and important to you than buying purchase drugs necessary for your health. Therefore, to save - no need to. You can save on books, trips to the cinema and theater, clothing, fashion and primambasah devaysakh on booze ... if you really really bad, then eat.

    The fact is that sometimes the difference between the price / quality does not lie in the range of normal consumer behavior. Sometimes (more often not) the quality is better "slightly", and the price is twice ...

    In the case of purchases of furniture, building materials, washing powder, probably not .... but to each address. But in the price / quality ratio in the case of drugs - the "quality" - is the quality of your one and only life + the risks of side effects and unpredictable course. Decide course you end up ... but I try not to risk a long time ....

    The most important thing - the predictability of drug action, predictability of possible side effects, predictable interaction with another medication, etc., etc.

    What is guided by a doctor? First of all, his personal experiences and information colleagues. Recently there was also "evidence" or "demonstrative" medicine allows an objective to combine the experience of many doctors, but it's a topic for another message, and it also has some pitfalls ....

    So, the experience of each doctor based on the use of a large, but in general the limited number of drugs, there's nothing to be done that's life. For the projected outcomes would be desirable to all, and be a guinea pig - to anyone.

    Narrated by a professional pharmacist:
    Oh, how sorry I am late to this topic has found, and then on the cheap analogs have a lot of interesting things to say.

    So, in a nutshell. We take the same, the first on the list, well, or the second or third, the sample is prepared by the chromatograph Sui - the output image - yum. The peak of the base material, a couple - three tiny spikes - and all the impurities of the case. Then take a cheap analog, exactly the same way we split into the device and ... Zazhmurivaemsya from the stockade all sorts of rubbish, which was crawling on the chromatogram.

    The point is that an expensive drug of default is made ​​from high quality raw materials, mostly American, Canadian or Israeli (well, sometimes even European, but it rarely is). A generic polls is brewed from the Sino-Indian stuff, miles sorry, so control of the raw material is much more approximate. Accordingly, at a minimum due to the impurities, we have gorgeous distortion mechanism of drug action. Raw-then controlled by a certain finite list of parameters, and inorganic impurities are tested in general is very conditional. And they can be there - Mama Do not Cry.

    In my personal ranking of the top position - the history of American aunt, who decided to Shibkikh emotions zaportit lot of aspirin, the reactor sharahnuv a decent dose of rat poison. Do you think, found in the production and control of pre-sale? A nifiga! Arsenic is a standard list of tests is not included, and if it is not specifically look for, what chance did you discover in life. Thank you, aunt of time changed his mind and gave the police had to withdraw from the sale of aspirin ... This is me simply to the fact that the inorganic "caught" very difficult, but trouble from it may be - Mama Do not Cry! And how many of the inorganics in the Indian and Chinese materials, which often made ​​in violation of the basic requirements of Good Manufacturing Practices, unknown to anyone at all.

    In general, this is my main professional peeve ... I apologize for the verbosity.

    Just sucks a cloud of years in the pharmaceutical production, including 10 years in Canada, I'm a little nervous react to the phrase "there is a cheaper analog of the same" because the answer to this - like Zhvanetsky "You are the ones that have, or those that are treated."
    Conclusion. If you do not trust the doctor, who appointed you, in your opinion, unjustified expensive / harmful / not the right treatment - do not worry, it happens. Only in such a situation it is necessary to change doctors, not prescribed to them. And if you trust the professionalism of the attending physician ... Please leave a creative approach to what the other area.







    BLACK LIST Roszdravnadzor


    Among domestic manufacturers:
    - LLC "Iodine Technology and Marketing" (45 episodes discarded four drugs)
    - Pharmaceutical factory in Tula (26 series of seven drugs)
    - JSC "Vifiteh" (22 Series of eight drugs).
    - OOO "Slavic pharmacy"
    - Integration of "biosynthesis", JSC
    - Tatkhimpharmpreparaty "
    - JSC "Rostov pharmaceutical factory»
    - JSC-Dalkhimpharm "
    - JSC "Biochemist"
    - Of "Flora of the Caucasus."


    Among importers:
    (List of heads of Indian pharmaceutical companies)
    - "Plethiko Pharmaceuticals Ltd."
    - "Shreya Life Sciences Pvt. Ltd. "," Drag Himalayya Co ".
    - The English company "Reckitt Benckiser Healthcare International Ltd." ("Boots Healthcare International")
    - The Ukrainian "Farmak"
    - The Belgian "YUSB SA Pharma Sector "
    - The Netherlands' Natur Produkt Europe BV "
    - Pakistan, "Pakistan Herbion Privet Limited"
    - The Belarusian Republican Unitary Enterprise "Belmedpreparaty"
    - The American "Sagmel Inc.".


    Medications most commonly Forge:
    (Name, number of detected counterfeits, the average retail price (USD):
    - Trihopol, 41 619, 39.5;
    - Mezim-fort, 9334, 40;
    - Valokordin, 8910, 60;
    - Festal, 8445, 156;
    - New-Passy (solution) 7622, ​​89;
    - Fort Essenciale-H, 5888, 235;
    - Claritin, 3153, 174;
    - Suprastin, 1040, 70.


    Into account the experts got a cure for schizophrenia, Abilify, manufactured by Bristol Myers Squibb Co. Clinical trials have shown to be toxic and harmful to the liver.

    The drug Xenical for weight loss by Roche Holding AG in connection with the risk of rectal bleeding.

    The list also includes anti-depressants - selective serotonin reuptake inhibitors and norepinephrine - in connection with the risk of congenital anomalies in children of persons receiving these drugs;

    Lamisil (antifungal drug) from Novartis AG from Roche because of the risk of mental disorders;

    Diovan, from high blood pressure medication, from Novartis AG-anemia;

    Plan B (the other name-Postinor and Escapelle)-oral contraceptives on the Israeli company Teva Pharmaceutical Industries - a high risk of loss of consciousness


    FORBIDDEN TO USE DRUGS
    Phenacetin - Forbidden medical use
    Cimetidine - medical use is prohibited
    Gemodez - medical use is prohibited
    Phenylbutazone (phenylbutazone) - Limited medical use
    Gentamicin - Limited medical use
    Nitrofuran (furatsilin) ​​- It is forbidden the use of medical tablet form orally
    Nitrofuran - Limited medical use
    Detoxification solutions that contain low-molecular polivinilpiralidon - Limited medical use
    Metamizole (analgin) - Limited medical use

    • limiting the age of the children when administered in tablet form - up to 12 years;
    • noted the group of patients whose risk of possible PR (burdened with a history of allergenic, blood diseases, disorders of the liver and kidneys);
    • duration of the continuous use of these drugs - not more than 3 days for all age groups (average therapeutic dose for adults 0.5 -1.0 grams);

    Rofecoxib (rofika, Denebol) - Limited medical use
    • limited the maximum daily dose (not exceeding 50 mg per day)
    • contraindication to the use of - people with an increased risk of the cardiovascular system (carried over heart attack, stroke, progressive clinical forms of atherosclerosis), age over 65 years.

    Thioridazine (sonapaks, ridazin) - Limited medical use
    • limited to the highest daily dose (no more than 300 mg per day)
    • Indications for use: limiting mental states psihonevrotichnye condition, mental disorders, alcohol genesis

    Eufilin - Forbidden medical use of medical forms, which contain a stabilizer ethylenediamine

    Drugs Nimesulide - Limited medical use
    • prohibit the use in children under 12 years of age;
    • concurrent use of potentially hepatotoxic means
    • Alcoholism, drug addiction
    • increased body temperature and flu-like condition

    Preprati oseltamivir (Tamiflu) - Amendments to the Regulations relating to the potential risk of neuropsychiatric disorders during treatment with Tamiflu, especially in children.


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