AUTOINFECTION

AUTOINFECTION (syn: autogenous infection, endogenous infection) - diseases caused by opportunistic autoflora, which is activated in conditions unfavorable for the body.

The causative agents of autoinfection are microorganisms inhabiting the skin and mucous membranes of the respiratory tract, digestive tract, genital organs, conjunctiva: staphylococci, streptococci, E. coli, proteus, klebsiella, fungi, etc. The main causes contributing to the occurrence of autoinfection are injuries with damage to the outer covers, Medical operations (operations, injections, endoscopy, catheterization of blood vessels), performed in violation of aseptic and antiseptic rules, congenital and acquired immune system disorders due to unfavorable ecology, stress, malnutrition, infectious (HIV infection, etc.), autoimmune, oncological And endocrine (diabetes mellitus) diseases, hypothermia, exposure to ionizing radiation, as well as the use of corticosteroids, cytostatic and immunosuppressive agents, irrational use of antimicrobial agents, leading to a violation of the microecology of the body (dysbacteriosis), i.e., the normal composition of the automicroflora.

Autoinfection can be manifested by local inflammatory processes (pyoderma, pneumonia , cholecystitis , pyelitis) and generalized infection until the development of sepsis.

Diagnosis is based on clinical data, the results of bacteriological investigation are desirable with the determination of the sensitivity of the isolated flora to antimicrobial agents.

The treatment of autoinfection processes is based on the elimination of the causes that triggered the activation of autoflora, the use of targeted antimicrobial therapy, bacteriophages, immunotherapy (eg, antistaphylococcal immunoglobulin), immunomodulators, eubiotics (bifidumbacterin, bifikol, biosporin, etc.) to restore the normal composition of the intestinal microflora, Endogenous infection (removal of carious teeth, tonsillectomy, etc.).