GANGRENE

HANGREN - one of the forms of necrosis (necrosis) of tissues. The cause of gangrene is more often damage to large arterial vessels, clogging them with a thrombus or embolus, vascular lesions in atherosclerosis, obliterating endarteritis, etc. The development of gangrene is promoted by prolonged spasm of blood vessels, increased blood clotting, chronic intoxication (alcohol, phosphorus, nicotine), starvation, frostbite , Endocrine diseases, especially diabetes , vitamin and cardiovascular insufficiency. Gangrene can occur in various tissues and organs, but gangrene of extremities is more often observed.

Distinguish dry and wet gangrene. With dry gangrene there is a picture of coagulative necrosis, mummification of the affected organ or tissue takes place. Wet gangrene occurs with the condition of putrefactive infection in the dead tissues. Under the influence of proteolytic enzymes, the tissues melt and take on the form of a fetid, dirty gray mass. At a wet gangrene the intoxication is sharply expressed.

In the treatment of dry gangrene, it is recommended to wait for the formation of a demarcation line (a clear boundary between necrotic and healthy tissues), and then amputate within healthy tissues. With gangrene of small parts of the body (nail phalanx, tip of nose, part of the auricle), dead tissue can separate itself. With progressive moist gangrene, an early amputation is necessary against the background of detoxification therapy.