CASTRATION - a condition arising from the complete and irreversible cessation of the function of the sex glands. May occur as a result of injury or infection, accompanied by the complete destruction of the tissue of the genital glands. In some cases, castration is a necessary measure and is included in the complex treatment of some serious diseases. Such castration is carried out only under strict medical reasons, surgically, using radiation or hormone therapy. In men, castration is performed surgically (removal of the testicles - orchiectomy) for malignant tumors of the testes, prostate gland. Women also more often undergo surgical castration (removal of the ovaries - ovariectomy) for malignant tumors of the ovaries, cervical cancer, breast cancer and certain other diseases. Less commonly, radiation castration is used - exposure of the ovaries to ionizing radiation at doses that cause the termination of their function. Hormone therapy with male sex hormones for the purpose of castration can be prescribed if there are contraindications to surgical and radiation castration, as well as in the late menopause and in menopause.
Castration in childhood leads to the greatest abnormalities in the body. Castration at reproductive age causes a number of metabolic, vegetative-vascular and other disorders characteristic of post-caracter syndromes. Castration in the late period of menopause and during menopause is not accompanied by significant changes in the body, since by this time the endocrine function of the sex glands is extinguished.