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PSYCHOTHERAPY
INVENTION
Patent of the Russian Federation RU2202379

METHOD OF CORRECTION OF THE PSYCHO-PHYSIOLOGICAL STATE OF THE ORGANISM

METHOD OF CORRECTION OF THE PSYCHO-PHYSIOLOGICAL STATE OF THE ORGANISM

The name of the inventor: Skvortsov Yuri Ivanovich ; Kodochigova Anna Ivanovna
The name of the patent holder: Skvortsov Yuri Ivanovich ; Kodochigova Anna Ivanovna
Address for correspondence: 410019, Saratov, ul. High, 22, ap. 11, AI Kodochugova
The effective date of the patent: 2001.02.22

The invention relates to medicine, namely to psychotherapy, and can be used to treat diseases of the cardiovascular system, in particular arterial hypertension. The hypnosuggestive effect is carried out and the state is monitored by recording a differential electrocardiogram. The ratio of the maximum rates of repolarization of the contractile myocardium is determined and the values ​​of the detected ratio are compared with the normal value. The detection of the ratio of the maximal rates of repolarization of the contractile myocardium is carried out simultaneously with the hypnosuggestive effect at least five times during one session: before the hypnosuggestive action, at the time of hypnosis, at the time of antihypertensive suggestion, at the time of withdrawal from the hypnotic state and after the hypnosuggestive effect . Compare the obtained values ​​with the control values ​​and determine whether the patient is in a state of hypnosis or in a state of wakefulness. The correction result is determined by the approximation of the obtained values ​​to the normal values ​​during the period of the purposeful suggestion and after the termination of the exposure. The method allows to increase the efficiency of correction due to the objectification of data characterizing the hypnotic state.

DESCRIPTION OF THE INVENTION

The invention relates to medicine, namely to psychotherapy, and can be used to treat a wide range of diseases of the cardiovascular system, in particular arterial hypertension.

A method of correction of the psychophysiological state of the organism is known (see RF patent 2033817, class A 61 M 21/00, published on April 30, 1995), which consists in the introduction of therapeutic information in a voice that changes in loudness, timbre, rhythm, Stage subnarcosis with a solution of ethyzole, and then - ketamine. The method allows treating and correcting various diseases, in particular, neurotic diseases.

However, it provides a suggestive effect against the background of the use of psychopharmacological agents when the stage of subnarcosis is reached. In addition, the method is not effective enough, as it does not provide an opportunity to objectively assess the degree of perception of information by the patient and is not intended to correct psychophysiological conditions in diseases of the cardiovascular system.

The method of correction of the psychophysiological state is also known (see RF patent No. 2071361, cl. A 61 M 21/00, published on January 10, 1997), which consists in recording the signals of the electroencephalogram, converting them into sound signals, Biological acoustic feedback. The method makes it possible to treat and correct the psychophysiological state of a person without a drug using a wide range of diseases, from hypertension to dysregulatory disorders in organic brain lesions and the cardiovascular system.

However, the method does not provide an opportunity to objectively evaluate the efficiency of the correction made. Criteria for assessing the psychophysiological state are, in particular, the heart rate, blood pressure, frequency and depth of breathing, which are not objective enough and depend on the individual psychophysiological characteristics of each person. In addition, the method is complicated in implementation, requires special equipment and, accordingly, additional costs.

The closest to the claimed is the method of correction of the psychophysiological state of the organism (see the thesis abstract for the degree of Candidate of Medical Sciences AI Kodochigova on the topic "Changes in psychosciences in patients with arterial hypertension and the possibility of their correction with non-drug treatment" / Saratov State Medical University - Saratov, 1999. - 22 p.), Consisting in the implementation of hypnosuggestive effects and status monitoring by recording a differential electrocardiogram, revealing the ratio of the maximum rates of repolarization of the contractile myocardium and comparing the value of the revealed relationship with the normal value. The method makes it possible to correct the psychophysiological states of the organism in diseases of the cardiovascular system, in particular arterial hypertension.

However, the method does not guarantee the objectivity of the obtained data, since it involves recording the values ​​of the ratios of maximum velocities only before the sessions of the hypnosuggestive action begin and at the end of them.

The invention is directed to the solution of the problem of increasing the efficiency of correction of the psychophysiological state of the organism by objectifying the obtained data upon introduction into the hypnosuggestive state.

To solve the task in the method of correction of the psychophysiological state of the organism, which consists in performing a hypnosuggestive effect and monitoring the state by recording a differential electrocardiogram, revealing the ratio of the maximum rates of repolarization of the contractile myocardium and comparing the value of the detected ratio with the normal value, according to the invention, the ratio of the maximum rates of repolarization of the contractile myocardium Carried out simultaneously with the hypnosuggestive effect at least five times during one exposure session, with the first time revealing the value of the relationship before the beginning of the hypnosuggestive effect, and then at the time of entering into the hypnotic state, at the time of antihypertensive suggestion, at the time of withdrawal from the hypnotic state and after The end of the hypnosuggestive effect, when the values ​​of the ratios approach the moment of antihypertensive suggestion and after the end of the hypnosuggestive effect to normal values, the correction of the psychophysiological state of the organism is judged.

The well-known sources of patent and scientific and technical information do not describe an effective method of correction of the psychophysiological state that allows to statistically reliably estimate the nature of the effect and to prove whether the patient is under hypnosis or in a state of wakefulness or in another kind of altered state of consciousness due to simultaneous registration in The process of one session of the suggestive effect of a differential electrocardiogram and the relationship of the maximum rates of repolarization of the contractile myocardium. Comparison of the values ​​of the relationship at the time of antihypertensive suggestion and after the end of the hypnosuggestive effect with normal values ​​of repolarization rates allows objectively to judge the correction of the psychophysiological state of the organism. This allows us to conclude that there is an inventive step in the claimed solution.

The invention is explained in the drawing, which shows the dynamics of the values ​​of the ratio of maximum velocities (OMS) in the group of patients treated with the claimed method (line 1), and in patients not hypnosuggestive (line 2).

The method is carried out as follows.

Before the beginning of the hypnosuggestive action with each patient an individual conversation is conducted, the content of which depends on the psychological characteristics of the individual, the educational qualification, the volume and nature of his ideas about hypnotherapy.

The hypnosuggestive exposure session was performed for 30 minutes in a darkened room in a supine position in a small group of patients (3-6 people). After a 10-minute rest, a differential electrocardiogram (ECG) of each patient was recorded and the ratio of the maximum velocities (OMS) of repolarization of the contractile myocardium was determined. The determination of this value was carried out using the technique proposed by E.Sh. Khalfenym, L.S. Sulkovskaya and V.A. Klotchkov (see, for example, the article of the authors "Diagnostic value of the study of the rate of change in the potential difference during the repolarization of the ventricles in patients with ischemic heart disease" / Journal of Cardiology .- 6. - 1978. - P. 55-62). OMS is the value of the first derivative of the ECG, calculated as the ratio of the amplitude of the second phase of the T wave to the amplitude of its first phase (in standard leads). The first derivative of the ECG was obtained by means of a differentiation attachment to a standard six-channel electrocardiograph.

After determining the value of OMS, patients were immersed in a hypnotic state by a verbal method to the level of the somnolent and cataleptic stage.

The therapeutic suggestion in the hypnotic state was carried out under specially selected music, the sounds of nature (the sound of the surf, the singing of birds, etc.). During the period of entering this state (at the 5-7th minute), the value of the CHI was repeatedly determined. Further, the value of OMS was determined at the time of the targeted antihypertensive suggestion (on the 15-17th minute), during the withdrawal from the hypnotic trance (at the 27th minute) and after the end of the session.

Obtained OMS values ​​(5 indices) were compared: first, with control ones - that is, with similar parameters of clinically healthy individuals who formed a control group; Secondly, with the indices of patients with arterial hypertension from the comparison group. This group included patients whose differential ECG recording was performed five times in the waking state at the same time intervals as in the patients treated with the hypnosuggestive method. Moreover, the comparison group was heterogeneous: the first subgroup was formed by individuals whose OMC repolarisations were detected under the same musical accompaniment used during the hypnotic session, and the second one without musical accompaniment (to clarify the influence of music on CHI).

All the results obtained were carefully analyzed using modern methods of mathematical statistics. It was found that the value of OMS repolarization in the group of healthy individuals was 1.57 ± 0.05 (P 0.05), which is consistent with the literature data, where it is shown: OMS are slightly dependent on age and sex, represent a stable parameter of electrophysiological properties of the myocardium and amount to ~ 1.6.

In patients with arterial hypertension (both in the main group and in the comparison group), the mean OMS repolarization was lower (P 0.01) than in healthy individuals.

Using the method of discriminant analysis, a diagnostic function was constructed that recognizes a group of patients who are in a state of hypnosis and who are not in a hypnotic state from the ratio of the maximum repolarization rates of the myocardium (P 0.05). By the method of multiple testing, statistically significant differences were found between the OMS values ​​at the individual stages of the hypnosuggestive session (P 0.01), while in patients who were not hypnosuggestive (both in the first and second subgroups of comparison), no repolarization dynamics were found in comparison with the initial ones. The method of multiple testing revealed significant differences between OMS in patients prior to the initiation of hypnoscience treatment and healthy individuals (P 0.05). At the same time, at the time of the purposeful hypnosuggestion effect with clinically healthy persons and after the end of hypnosuggestive therapy with persons of the control group, such differences were not established.

When the revealed values ​​of OMS at the moment of antihypertensive hypnosuggestion to control with an accuracy of up to 0.1 and after the end of hypnosuggestive treatment, to the indices of healthy individuals to within 0.1 are judged about the positive correction of the psychophysiological state and the reliability of the hypnotic effect.

The method was tested in the clinic of the Saratov State Medical University at the Department of Propaedeutics of Internal Diseases (on the basis of the Municipal Medical Institution of the 2nd City Clinical Hospital named after VI Razumovsky) for 134 patients with arterial hypertension and 20 clinically healthy individuals.

In all patients with arterial hypertension, a statistically significant decrease in OMS values ​​of myocardial repolarization was noted in comparison with healthy individuals (P 0.01). After the end of the course of hypnosuggestive sessions, in all patients there were no significant differences compared to the control ones, which could not be said about those who did not receive hypnotherapy (P 0.05).

Moreover, the trend toward normalizing the indices of OMC of myocardial repolarization was already outlined at the time of entering into the hypnotic state and was maximally expressed during the purposeful suggestion (P 0.01), and after the end of the hypnosuggestive effect (P 0.05).

From the results of the studies presented in the figure, it is seen that in patients receiving hypnosuggestive treatment, against the background of a hypnosuggestion session, changes in the OMC of repolarization with a tendency to normalization already at the time of entering into the hypnosuggestive state are noted and are as pronounced as during the targeted suggestion and after the end Treatment session (line 1).

As for patients from the comparison group, they did not show any dynamics of OMS compared to the baseline (line 2).

Example 1 . Patient A., 39 years old, suffered for 10 years with essential arterial hypertension. At admission, he complained of headaches, dizziness, general weakness, sleep disorder. Objectively: the left border of relative cardiac dullness is shifted to the left by 1.5-2 cm; Heart sounds are rhythmic, heart rate is 82 beats. In min, the accent of the second tone on the aorta, the pulse is intense, large in magnitude, AD - 160/100 mmHg. (On both hands); On ECG - signs of hypertrophy and overload of the left ventricle; On a differential ECG - OMS = 1.18; Ophthalmologist noted changes in the fundus: angiopathy of the retina of both eyes. A diagnosis was made: Stage II hypertension.

The patient underwent hypnosuggestive treatment (10 sessions as described above). After the first session: subjectively - some improvement in the state of health, the intensity of headaches decreased, the BP figures decreased to 150/90 mm Hg. After the third session: he does not complain; AD-120/70 mmHg, pulse of satisfactory qualities, rhythmic, 64 beats. In minutes; Normalized night sleep; The signs of left ventricular overload decreased on the ECG.

Later, there was a significant decrease in the level of anxiety, increased efficiency and better mood; BP was stored on the numbers 120/70 mm Hg. Art. The dynamics of OMS values ​​in this patient is shown in the table.

In a satisfactory condition, the patient was discharged from the hospital after completing 10 hypnosuggestive sessions, the last of which was aimed at fixing the resulting therapeutic effect. Subsequently (during the first half of the year) the blood pressure did not rise above 130/80 mm Hg. (Fluctuated within 110 / 70-130 / 80 mm Hg), the state of health remained good without taking antihypertensive drugs. CHI remained at the level of healthy persons (after 6 months OMS = 1.59).

Thus, the claimed method makes it possible to objectively assess the presence of a hypnosuggestive state of consciousness and effectively perform a correction of the psychophysiological state of the organism, in particular in arterial hypertension.

CLAIM

A method for correcting the psychophysiological state of an organism in arterial hypertension, including hypnosuggestive action and correction control by recording a differential electrocardiogram, calculating the ratio of the maximum repolarization rates of the contractile myocardium (OMC), and comparing the values ​​obtained with the norm, characterized in that OMC is determined at least 5 times during One session before the initiation of the hypnosuggestive effect, when entering the hypnotic state, during the purposeful suggestion, when exiting the hypnotic state and after the hypnosuggestive action, compare the obtained values ​​with the control ones and determine whether the patient is in a hypnotic state or in a state of wakefulness, and the result of correction of the psychophysiological States are determined by approximating the values ​​of OMC to normal during the period of purposeful suggestion and after the end of the exposure.

print version
Date of publication 06.01.2007gg