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INVENTION
Russian Federation Patent RU2283059
METHOD OF SURGICAL TREATMENT OF NSCLC
Name of the inventor: Kosenok Victor K. (RU); Beloved Mikhail Sergeyevich (RU); Beloved Alex S. (RU); Voronov Oleg E. (RU)
The name of the patentee: Omsk State Medical Academy (RU)
Address for correspondence: 644099, Omsk, ul. Lenin, 12, OSMA, patent department
Starting date of the patent: 2004.07.05
The invention relates to medicine and can be used in the treatment of NSCLC surgically. To this end, during the removal operation produce fiber removal or resection within healthy tissue of the affected organ. Thus lymph nodes regional metastasis zones before removing frozen to - 5-10 ° C. The method reduces the possibility of the implantation and lymphogenous metastasis by choosing such local mode cryoablation at which freezing occurs capsule lymph nodes and ducts extending from them to the specified temperature, allowing to observe the principle of ablation.
DESCRIPTION OF THE INVENTION
The invention relates to medicine and can be used in surgical practice.
There is a method of surgical treatment of non-small cell lung cancer, including removal of the affected organ or resection within healthy tissue (Blokhin, B.E.Peterson. Clinical Oncology // Moscow, Medicine, 1971, str.43-49) .
There is a method of surgical treatment of non-small cell lung cancer, including removal of the affected organ or resection within healthy tissue with fiber and lymph nodes zones of regional metastasis (A.H.Trahtenberg, V.I.Chissov. Clinical onkopulmonologiya // Moscow, GEOTAR Medicine 2000 , at str.337-356).
There is a method of surgical treatment of non-small cell lung cancer, which comprises removing the first stage and lymph node tissue zones of regional metastasis, followed by removal or resection within healthy tissue of the affected organ (G.Massard, M.Riqued. Proceedings of the Congress of Thoracic Surgeons and the cardiovascular surgeons. Marseille 2002 , at str.87-88).
The main disadvantage of surgical methods of treatment for a violation of the integrity of the capsule is non-small cell lung cancer lymph node dissection during the classical and the seeding of the chest cavity cancer cells, which leads to a decrease in radical surgery, early retsedivirovaniyu disease.
Object of the invention is to prevent contamination by cancer cells of the thoracic cavity.
The problem is solved in that in a method of surgical treatment of NSCLC, comprising removing tissue and lymph nodes zones of regional metastasis, removal or resection within healthy tissue of the affected organ, lymph nodes prior to removing the frozen - 5-10 ° C.
Method is as follows
During surgery for non-small cell lung cancer patient is under endotracheal anesthesia, thoracotomy is made, the audit of the pleural cavity. to -5-10 ° C, at which the freezing capsules lymph nodes and exhaust ducts from them before the local lymph node dissection is performed freezing nodes using "Cryoelectronics 2" unit. The refrigerant (liquid nitrogen) enters the device tip, cools it, and it, in turn, promorazhivaet lymph node. Temperature control thermocouple. When freezing lymph nodes retained the integrity of the capsule at the time of dissection, thereby complied with the principle of ablation. This prevents colonization of the chest cavity cancer cells and reduces the likelihood of retsedivirovaniya disease. At first lymph node dissection is carried out, then remove the tumor directly. The presence of abnormal cells in the thoracic cavity control cytology wash water, but also smears the walls with the lymph nodes, and their bed, obtained during surgery, before and after the step of lymphadenectomy.
Example. Patient K., 52 years old, was admitted to the Thoracic Department OOOD diagnosed with cancer of the peripheral upper lobe of the right lung T3N2M0, Article III A, Cl. column 2. In the context of thoracic surgery department performed right pneumonectomy with lymph node dissection. The wash waters before and after dissection has been detected abnormal cells. During the operation in the mediastinum revealed dense, increased (up to 3 cm), deformed lymph nodes. After local freezing "Cryoelectronics 2" machine lymph nodes removed. The washings atypical cells detected. Histologically damage the capsule of the lymph nodes were found in the sites themselves - metastases in smears were found by cytological study of atypical cells.
This method of treatment used in the clinic at 10 persons suffering from NSCLC. Retsedivirovanie process was observed in one patient.
The advantage of this process over known reduction is lymphogenous metastasis and implantation, reduction and relief equipment runtime phase lymphadenectomy, reduction of blood loss during surgery, and a reduction lymphorrhea during and after surgery.
CLAIM
A method of surgical treatment of non-small cell lung cancer, which comprises removing tissue and lymph nodes zones of regional metastasis, removal or resection within healthy tissue of the affected organ, characterized in that before removal of the lymph nodes were frozen to - 5-10 ° C.
print version
Publication date 06.01.2007gg
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