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DERMATOVENEREOLOGY
INVENTION
Patent of the Russian Federation RU2245114

METHOD OF CRYOGENIC TREATMENT OF SKIN

METHOD OF CRYOGENIC TREATMENT OF SKIN

The name of the inventor: Kochenov V.I.
The name of the patent holder: GU "Nizhny Novgorod State Medical Academy" (RU); OOO Center for Medical Cryology "onKolor" (RU); Kochenov Vladimir Ivanovich
Address for correspondence: 603005, Nizhny Novgorod, ul. Alekseevskaya, 1, NGMA, Patent and Licensing Department, E.K. Pavlova
Date of commencement of the patent: 2003.02.10

The invention relates to the field of medicine, in particular to cosmetology and dermatology. The method makes it possible to obtain a stable, pronounced and prolonged cosmetic effect without the risk of complications. Preliminary treatment of the skin and direct exposure to the skin with a swab soaked in liquid nitrogen are carried out. Before treatment, the skin is treated with alcohol-free cleansing and moisturizing agents, the treatment begins with cryodestruction of pathological lesions and pigment changes, then 2-3 test applications are made using A tampon with a characteristic relief pattern of the surface, select the optimal exposure mode for cryoexposure upon appearance and disappearance of a characteristic pattern of the tampon for 1-3 seconds on the white surface of the skin, the treatment is performed first on the most open and then on less accessible areas of the skin surface, using alternately Sets of tampons of different diameters and with different values ​​of the relief pattern, each applicator is operated continuously for 2-5 seconds, the procedure with each applicator is repeated 3-5 times, after the appearance of uniform hyperemia, cryoversion is repeated in the same sequence, the session is continued for 40 minutes - 1 hour, at the end of the session the skin is treated differentially with nutrients and medicines, the treatment is repeated after 1-3 months.

DESCRIPTION OF THE INVENTION

The invention relates to the field of medicine, namely to cosmetology and dermatology, and can be used for preventive and curative effects on the skin, primarily on the face and neck, to improve the appearance and rejuvenation of the skin, smooth wrinkles, anti-inflammatory, decongestant, stimulating regeneration Effect, and for the elimination of dermatitis, small vascular, pigmentary, tumor, papillomavirus, herpetic, fungal and other lesions.

One of the most promising in modern medicine in general and in non-surgical skin treatment, in particular, is the cryogenic method using ultra-low temperature liquid nitrogen.

Even with a very short-term freezing of the skin, therapeutic therapeutic effects occur: the peeling of the horny layers of the skin is facilitated, the pores and sebaceous glands are opened and cleaned, the dynamics of the tone of the blood vessels is optimized, the red blood vessels are opened, the blood and tissues are oxygenated, the lymph flow increases, Phagocytic activity of leukocytes, regeneration is accelerated. A more prolonged freezing makes the pathogenic viral, microbial, fungal elements in the focus of the pathological process unviable and alien, facilitates the finding of their antigenic structures, triggers the mechanism of production of specific antibodies. In the case of metabolic disorders or allergic lesions, the freezing of the tissues of the focus makes only the inherent antigen + antibody + complement complexes foreign to the organism. Rapid freezing of any biological tissue below -60 ° C or several times to -20 ° C causes its irreversible death - cryonecrosis. Cryonecrotic tissue is rejected gradually, as the healthy epithelium regenerates under cryonecrosis, without blood, without the formation of appreciable scarring. There is no inhibition of hematopoiesis and immunity, on the contrary, their stimulation is observed. Thus, cryodestruction is the most physiological way of obtaining necrosis of pathological tissue, since lethal negative temperatures are created locally in the volume of pathological tissue. It is noteworthy that these therapeutic effects are present in one way or another with different methods of cryoexposure. That is why the cryogenic method belongs to the category of the most universal and effective both in therapeutic and in surgical treatment.

Known is a method for treating various skin diseases by immovably pressing to the pathological focus of a cotton swab dipped in liquid nitrogen (Chernyshev IS RF Patent No. 2000088. The method for treating psoriasis., Registered June 11, 1993). In a similar way, it is customary to use a cryogenic method in the treatment of warts, calluses, keratoses, and the like. (Chernov PN, Slepkova LK Treatment of some diseases and cosmetic defects with liquid nitrogen .- Methodical recommendations, www.cryotec.ru). It involves prolonged freezing of tissue in the same place with a cotton swab dipped in liquid nitrogen. At the same time, the temperature of the tissue falls to the lethal values ​​for it, and then comes the onset of cryonecrosis. But due to prolonged exposure there is frostbite, a cold burn, bubbles appear, not only in the pathological focus, but also nearby, on the surface of healthy skin. Such a method can not be used in health-improving cosmetic procedures as a light, superficial, non-damaging method, since the appearance of the skin after such a freezing deteriorates for a long time, the skin acquires cosmetic defects.

As a prototype of the present invention, a method for cryogenic skin treatment has been chosen, which includes pretreatment of the skin and direct exposure to the skin with a swab dipped in liquid nitrogen (Papias NA Methods of correction of cosmetic defects .-- Medical Cosmetics: A Practical Guide for Physicians. , Revised and supplemented, Minsk, publishing house "Belarus", 1999. Chapter 2, pp. 43-47). This method of cryogenic treatment of the skin is also called cryomassage. At its realization preliminary process a skin with alcohol, degrease it, do dry. With a wet cotton swab moistened with liquid nitrogen, the skin of the face and neck are stroked over the dermal lines, sliding in circular motions, without pressure and stops. The duration of the cryomassage session is from 30 seconds to 1-2 minutes. Observe the local skin reaction, which, in the optimal version, should turn pink. When there are unpleasant sensations, the session is stopped. The session is repeated daily or 2 times a week, 10-20 sessions per course.

Despite the fact that the method described as a prototype is used in many beauty salons to improve the appearance of a face and treat a whole range of skin diseases, it is characterized by a number of drawbacks.

In contact with the skin surface, directly lead a cotton swab - a lump of wool, having an uneven surface with unavoidable separate areas of swelling or densification of cotton material. These sites have a significant area of ​​several square millimeters and the corresponding volume. If cotton wool, moistened in liquid nitrogen, stop even for a moment pressed against the skin, then over the entire contact area a continuous freezing zone quickly appears. In addition, the smallest fibers of cotton wool are frozen to the exit zones from fat and sweat glands, adhere to their contents, break away from the swab. In the course of the procedure, lacrimation is often initiated, adhesion of fibers with a moist surface of tears occurs. In these places, too, too much cooling, a deep uncontrolled freezing occurs against the background of a relatively small cooling of the entire surface of the skin, which causes the appearance after the procedure of irreversible cryogenic deformations and negative reactions in the form of bubbles on the skin, a cosmetic defect requiring special treatment.

To limit the occurrence of adhesion, the skin before cryomassage is wiped with alcohol. This causes damage to the skin, it withers it. Especially it is unacceptable to use alcohol in patients with thin, delicate and dry skin, which is the most often shown cryogenic curative and preventive effect. For this reason, after the session, almost always within a few days, there is visible peeling of the skin, which requires special treatment.

In the prototype method, the tampon is moved linearly on the skin or in circles, and the handle remains during the procedure oriented almost at the same angle to the skin surface, causing mechanical deformation of the skin with displacement and folds in the direction of movement of the tampon. This has a negative effect on the therapeutic effect, especially in cases where the purpose of exposure is precisely the prevention of wrinkles.

Surface sliding, stroking the skin with a swab without stopping and pressing does not help achieving the basic condition of cryogenic treatment - short-term glaciation of the skin tissue with the formation of interstitial ice. In addition, with constant contact of the same side of the tampon with ever newer and newer skin patches on this side of the tampon surface, there naturally results in a lack of negative temperature to ensure a short-term freezing effect. Therefore, in the prototype method, when cryo-exposure is achieved, only cooling and blanching of the skin is achieved, and not the formation of a real freezing zone, which is characterized by a sharp whitening, icing of the skin. Almost in the method-prototype of the real freezing zone even avoided, because they fear complications after the procedure in the form of bubbles.

In the prototype method, the same tampon is used for the procedure. However, the microconfiguration of the skin in different anatomical zones, especially on the face, is not the same. Elasticity, thickness, blood supply to the skin, the number and size of sebaceous and sweat glands, hair pouches and are very diverse. Equally qualitatively, cryogenic treatment with the same tampon and on the forehead, and on the eyelids, and in the nasolabial fold area is impossible, since it is impossible to create an adequate thermal contact between the same tampon and the skin surface on the entire face or neck. The areas of skin on the face that are most in need of cryogenic treatment (eyelid, nasolabial fold, lip) remain poorly accessible, and, on the contrary, separate healthy areas are unreasonably often hit and excessively damaged by the cold zone, as there is no differentiated approach to different areas of skin that have Special, characteristic structure of the surface and glands.

In addition, the profile of the curvature of the surface of the facial skin in patients is individual. The goals of cryogenic treatment can be different: in some cases it is the elimination of wrinkles, in others - the removal of inflammation and others. But in the prototype method there is no individualization of the selection of tampons depending on the purpose of treatment, gender, age, nationality of the patient.

The structure of the cotton swab is such that, in repeated exposures, the skin surface is preferably cooled by the same sealed portions of the same size and almost completely lacks cooling by the most loose places of the tampon. As a consequence, it becomes impossible to achieve uniformity of the cooling curative effect by the prototype method for diffuse pathological changes.

The prototype method does not provide cryo-therapy for protruding (exophytic) formations (acrochords, papillomas, etc.), because when cryoactive, they contact the warm healthy skin around the leg, deforming and cooling only from the outside, which is clearly insufficient for their complete cryodestruction . Moreover, in the presence of neoplasms, cryomassage stimulates their growth.

In the prototype method, the cryomassage session is terminated with the appearance of the first local reactions of the skin in the form of porosity or subjective unpleasant sensations of the patient, there are no clear, objective criteria for monitoring the cryoprocedure, assessing the cryoexposure zone, exposing cryoexposure, which makes it difficult to assess the quality and effectiveness of the treatment as a whole.

Thus, the known method of treatment does not provide enough deep and even cooling of the skin, does not allow to obtain a pronounced and persistent therapeutic effect. The method is traumatic, can cause complications and negative, from the point of view of cosmetology, skin reaction, requires frequent repetition.

The objective of the proposed method of cryogenic treatment of skin diseases is to obtain a pronounced, stable and prolonged therapeutic and cosmetic effect without the risk of complications, preventing the appearance of visible peeling of the skin after the procedure, excluding the formation of bubbles on the skin, achieving dosed, discrete, localized, deeper and, ultimately , A uniform real freezing of the skin, with the direct formation of interstitial ice.

The task is achieved by the fact that, in a known method of cryogenic skin treatment, including its preliminary treatment and direct exposure to the skin with a swab soaked in liquid nitrogen, the skin is treated with alcohol-free cleansing and moisturizing agents before the onset of exposure, treatment begins with cryodestruction of pathological foci and pigment changes, Then make 2-3 test applications using a tampon with a characteristic relief pattern of the surface, select the optimal exposure mode for cryoexposure by appearance and disappearance for 1-3 seconds on the white surface of the fingerprint of the characteristic pattern of the tampon, the treatment is performed first on the most open ones, and Then on less accessible areas of the skin surface, using alternately sets of tampons of different diameters and with different values ​​of the relief pattern, each applicator is operated continuously for 2-5 seconds, the procedure with each applicator is repeated 3-5 times, after the appearance of uniform hyperemia, cryoversion is repeated in The same sequence, the session is continued for 40 minutes - 1 hour, at the end of the session the skin is treated differentially with nutrients and medicines, the treatment is repeated after 1-3 months.

The proposed method meets the criterion of the invention "novelty", because as a result of the conducted patent information studies, no sources that discredit the novelty of the invention have been identified.

The proposed method meets the criterion of the invention "inventive level", since it has not been revealed that there are significant differences in the proposed method in similar solutions.

The parameters and time of exposure to the skin were selected from the results of experimental studies, taking into account their immediate evaluation in each patient.

The method was tested in the laboratory of medical cryology of NGMA and OOO "onColor" in cryogenic treatment in more than 80 patients with various skin pathologies: eczema, neurodermatitis, acne, herpes, mycoses, hyperkeratoses, senile pigment changes, papillomatosis, acrochords, telangiectasias and t .P. The method is applied to more than 120 people with cosmetic purposes: with aging face skin fading, with progressive wrinkling of the skin, dissatisfaction with the appearance of the skin of the face, skin rejuvenation, activation of regeneration, cleansing, smoothing of the skin. All patients received excellent therapeutic and cosmetic results.

The proposed method provides:

  • Pronounced, persistent, prolonged medical, revitalizing and cosmetic effect;
  • The ability to control the quality and effectiveness of treatment due to the presence of clear criteria for assessing the zone and exposure to cryoexposure;
  • Individual and differentiated approaches to treatment;
  • Rapid and non-traumatic skin freezing;
  • Dosed, with the possibility of clear localization, and, ultimately, a uniform and deep freezing of the skin;
  • Creation of discrete, linear, non-merging freezing zones, with the direct formation of interstitial ice;
  • Complete cryosurgical destruction (cryodestruction) of individual small pathological, exophytic and diffuse formations, pigment changes;
  • The possibility of multiple real freezing of the skin without the risk of complications and cosmetic defects (blistering on the skin, peeling of the skin) after the procedure.

The method is carried out as follows. Before krioprocedure, sets are prepared, for example, of spherical cotton swabs that do not lose elasticity at liquid nitrogen temperature, in casings made of natural material (fabric - cotton, wool - with a relief-checkered (waffle) structure, or woven, or mesh or perforated leather) . Shells have cells of different sizes, for example, such a structure that the thickness of the wall between the cells does not exceed 1/10 of the size of the side of the cell, and the depth of the cell is not less than 1/5 of the side dimension. Diameters of applicators can be related for convenience to known morphological features of a person's face, for example, with the size of the eye gap. Sets include tampons of at least three sizes: with diameters corresponding to the entire length of the patient's eye slit, 1/3 and 1/5 of the length of the optic gap. For 3 tampons of the same diameter, the shells are selected so that the cell size is 1/10, 1/20 and 1/30 of the circumference of this tampon for each tampon, and so for tampons of all 3 diameters, which follows from their practical use . Wadded lump tightly crumpled, covered with a stretch of a piece of material until the formation of a spherical swab. Fixation of the tampon is carried out, for example, by grasping the collected tissue elements with the hemostatic clamp at the proximal part of the tampon. The tampon is fixed on a non-heat-conducting handle.

The face of the patient is treated with a non-alcoholic cleanser. Then put on the skin and lightly rub the moisturizer. They wait 10-15 minutes.

Then all tampons are immersed in liquid nitrogen, poured into thermos with the necks of the corresponding diameter. After stopping the rapid boiling of liquid nitrogen tampons are ready to work.

First of all, special applicators perform cryodestruction of individual small pathological foci (inflammations, dermatitis, papillomas, keratoses, acrochords, nevuses, hemangiomas, etc.) and multiple point cryodestruction of pigment changes.

Then, with a swab of the largest diameter and with the largest cell, we make trial applications in those places where there is a fairly open and flatter skin surface: in the forehead, temporal, cheek, chin, chin and neck. Remove the tampon from liquid nitrogen, remove its excess from the tampon. Touched by the side surface of the tampon to the skin. Immediately begin to swab the tampon, pressing on it with the formation of a slight deflection of the skin and the surface of the swab, stretching the skin. The handle is oriented at this almost flat, at a very sharp angle to the surface of the skin. The handle makes an arcuate, almost 180 °, rotation over the skin from the center of the tampon. Thus, the tampon is rolled to a distance almost equal to half the length of its circumference. Average time for moving the tampon is about 2-3 or 3-5 seconds, depending on the type of skin (tender and thin or thick and oily skin). After the rotational rolling of the tampon, an elongated elliptical relief imprint-the freezing zone-remains behind it.

The surface of this zone is examined using a binocular lens and fiber optic lighting, and its characteristics are evaluated. Perform 2-3 test applications with rolling the tampon at different speeds, with a change in the angle of the handle. Compare the characteristics of the obtained zones. Select the optimal rolling speed of the tampon, in which the structure of the freezing zone fully corresponds to the characteristic pattern of the tampon shell. The imprint disappears from the skin surface due to natural heat transfer. Control the thawing time, which should be no more than 1-3 seconds.

With the chosen optimal speed continue treatment on the forehead, temples, cheeks, chin, under the chin and on the neck, while:

- one tampon is carried out 3-5 applications, then it is re-immersed in liquid nitrogen for 5-10 seconds, squeezed and used further;

- The direction of rolling the tampon during the cryoexposure on the same section of the skin surface is changed in the direction of the wrinkles (along the elastic fibers) and short movements perpendicular to them.

After all the most exposed areas are subjected to a cryoprotection with a tampon with cells in 1/10 of the circumference, the same areas are treated with tampons with cells in 1/20 and then in 1/30 of the circumference of the tampon. As a result, after 5-10 minutes of exposure to the skin, noticeable hyperemia is noted, which is manifested by oblong stains on the places that were first exposed to cryo-exposure. Subsequent cryo-effects are oriented to those areas where the hyperemia is less pronounced or has not yet arisen, that is, the expansion of the vasculature has not yet occurred to an adequate degree.

Hyperemic sites are treated repeatedly up to 3-5 times with large tampons with different cells.

In the treatment of less accessible areas of the skin of the face (parotid, superciliary, nose, on the outer nose, around the nostrils, near-lips, on the eyelids, in the regions of the inner and lateral corners of the eye), the following procedure for the use of applicators is realized.

First, cryo-action is carried out with tampons with large (in 1/10 of the length of the circumference) cells: a swab with a diameter of 1/3 of the length of the eye gap processes the skin in the superciliary region, near the nose, in the parotid and near-humeral areas, at the external nose; A tampon with a diameter of 1/5 of an eye crack is treated by the skin near the wings of the nose, at the nostrils, on the eyelids, in the region of the inner and lateral corner of the eye; The same swab is affected along the direction of the most pronounced wrinkles on the skin. In this case, beforehand, the skin is stretched by the other hand in the direction perpendicular to the tampon rolling line, pushing and straightening the wrinkled tissues and opening the "bottom" of the wrinkle for cryoexposure. Be sure to achieve the formation of the relief-checkered freezing zone and on the "bottom" of the wrinkle. Then, the effects on the less accessible patches of the same diameters are repeated, but with smaller cells up to 3-5 times.

The relief zones of cryoexposure with tampons of different sizes overlap each other, an absolutely clear boundary between them is not differentiated. Continuous "checkered" fine-focal real freezing allows you to repeat cryo-exposure on the same skin area without fear of bubbles after the procedure. A sign of a sufficiently intensively produced therapeutic cryoexpression is the occurrence of persistent and uniform skin hyperemia. As the hyperemia increases during cryotherapy, the facial skin becomes hotter, the intensity of the blood flow increases. Therefore, the actual exposure to cryo-exposure to maximally hyperemic skin is increased without the threat of complications. Several times the cryoapplications are repeated with the corresponding tampons with different cells, while the swabbing speed of the tampon is somewhat reduced, thus increasing the exposure of freezing at each point of the skin surface. The most often repeated freezing of those areas of the skin surface, where there are exophytic pathological foci (acrochords, papillomas, etc.). For this, tampons are taken with cells slightly larger than the diameter of the exophytic part. Puncture of the tampon for exophytic formation is stopped when it is found full icing, the so-called "drainage zone" of freezing that ensures its complete cryodestruction.

The cryotherapy session is continued for 40 minutes - 1 hour.

Immediately after all cryoapplications, nutrient, regenerating, repairable agents (in the form of creams, gels, balms) are applied to healthy hyperemic skin, and appropriate medicinal substances (antiseptics, antifungal, antiviral, proteolytic enzymes, mainly in the form of ointments) are placed on the sites of diffuse pathological changes. For 1 hour. After removing the cream, the complete disappearance of the hyperemia of healthy skin, purification of the pores, smoothing of wrinkles, fresh and healthy appearance are noted. Mark the gradual disappearance of pathological changes within 2-3 weeks. The cryogenic treatment session is recommended to be repeated no earlier than a month later.

Examples illustrating the possibility of carrying out the invention.

Example 1 . The patient KAG, age 41, turned 21.10.2001 to the laboratory due to dissatisfaction with the appearance of the facial skin, the presence of hyperkeratoses, sloughing epidermis on the skin of the forehead and cheeks, the recurring foci of mycotic dermatitis, the progressive wrinkling of the skin near the eyes, On the forehead, neck, the presence of visible, filled with pore contents of the sebaceous glands on the skin of the back, the wings of the nose and the chin, often arising herpetic eruptions on the upper, lower lip and skin under the lip, the presence of multiple small acrochords on the skin of the neck. After treatment of the face and neck of the patient with cleansing lotion, first of all special cryoapplicators performed cryodestruction of hyperkeratoses, foci of dermatitis on the face and small acrochords on the neck.

Then, with a swab of the largest diameter and with the largest cage, trial applications were made in the forehead, temporal, cheek, chin areas. The tampon was removed from liquid nitrogen, its excess was removed from the tampon. Immediately began rolling the tampon on the surface of the skin, pressing on it with the formation of a slight deflection of the skin and the surface of the swab, with kneading of the skin, for about 2-3 seconds on the forehead, temples, cheeks, that is, in areas with dry skin, and 3- 5 seconds - on the chin, where the skin is high fat, until the appearance of elliptical relief checkered prints. Three times the tampon was rolled at different speeds, with a change in the angle of inclination of the handle. The freezing zones were evaluated from the point of view of the correspondence between the characteristic cellular pattern of the tampon shell. Controlled the time of thawing and disappearance of the print, which was not more than 3 seconds. With the chosen optimal speed, continued treatment with a large tampon on the forehead, temples, cheeks, chin, under the chin and on the neck, with one application using 3-5 swabs, then re-immersed in liquid nitrogen for 5-10 seconds, squeezed and used Further; The direction of rolling the tampon during the cryoexposure on the same section of the skin surface was changed in the direction of the wrinkles (along the elastic fibers) and short movements perpendicular to them. Further, the same sites were treated with tampons with cells in 1/20 and then - in 1/30 of the circumference of the tampon. After 5 minutes, on the sites that had been subjected to cryo-exposure first, noticeable hyperemia appeared in the form of oblong stains. Subsequent cryotherapy was performed where hyperemia was less pronounced or had not yet occurred. Hyperemic sites were then re-treated up to 5 times with large tampons with different cells.

Next, a tampon with large (1/10 of the length of the circumference) cells and a diameter of 1/3 of the length of the eye slit was treated in the skin in the brow region, near the nose, in the parotid and near-humeral areas, at the outer nose, with a swab with large cells and a diameter of 1 / 5 of the eye gap - the skin near the wings of the nose, at the nostrils, on the eyelids, in the region of the inner and lateral corner of the eye; A tampon with large cells and a diameter of 1/5 of the eye slit acted along the direction of the most pronounced wrinkles on the skin, with the other hand pulling the skin in a direction perpendicular to the tampon rolling line until the formation of a relief-check freezing zone on the wrinkle "bottom".

Repeated the effects on the same sites with tampons of the same diameters, but with smaller cells, 3 times.

Further on, the hyperemic skin was repeated 3 times with cryoapplications on the whole surface of the skin of the face and neck with corresponding tampons, starting with a large one, with cells of different sizes, while the swelling rate of the tampon was somewhat reduced, increasing the cryoexposure exposure. 3 times the freezing of hyperkeratoses was repeated, and the acrochords on the neck until they were completely iced. The cryotherapy session was continued for 1 h 10 min.

After cryotherapy, a regenerating cream was applied to the healthy hyperemic skin, and an antiseptic ointment was applied to edematous areas of pathological changes. After removing the cream after 1 hour, there was a disappearance of hyperemia, smoothing of fine wrinkles, purification of the pores, healthy skin obviously acquired a more recent appearance; For sites that underwent cryodestruction, swelling and redness were characteristic. On the 2nd day after the procedure, the swelling of the existing pathological formations and skin peeling disappeared, after 2 weeks the cryonecrotic tissues of the existing small pathological formations were completely rejected, after 1 month, redness almost completely disappeared in the areas of the existing pigment and pathological changes. Cryotherapy was repeated after 1.5 months. A pronounced rejuvenating and healing effect of the procedure was noted. No complications in the form of blisters and scars, relapses, and complaints from the patient after treatment is not.

Example 2 . Patient Sh. MV, age 52, applied to the laboratory on 29.09.2002 for extensive pigment changes in the skin of the face in the cheek area, the presence of nevuses on the forehead in the superciliary area, multiple papillomas on the eyelids and neck, and in connection with Dissatisfaction with the appearance of the skin (general dryness with increased porosity of the T-shaped region - the middle part of the forehead, wings and the back of the nose, chin), progressive wrinkling of the skin around the eyes, lips and neck. After treatment of the face and neck of the patient with cosmetic milk, special cryoapplicators performed a cryodestruction of nevi and papillomas, followed by multiple point cryodestruction of pigment changes.

Then, with a swab of the largest diameter and with the largest cage, trial applications were made in the region of the forehead, cheeks, chin. The tampon was removed from liquid nitrogen, its excess was removed from the tampon. Immediately began rolling the tampon on the surface of the skin, pressing on it with the formation of a slight deflection of the skin and the surface of the swab, with kneading of the skin, for about 3-5 seconds on the forehead and chin, that is, in areas with high fat content, and 2-3 seconds - on the cheek, where the skin is dry, before the appearance of elliptical relief checkered prints. Three times the tampon was rolled at different speeds, with a change in the angle of inclination of the handle. The freezing zones were evaluated from the point of view of the correspondence between the characteristic cellular pattern of the tampon shell. Controlled the time of thawing and disappearance of the print, which was not more than 3 seconds. With the chosen optimal speed, continued treatment with a large tampon on the forehead, temples, cheeks, chin, under the chin and on the neck, with one application using 3-5 swabs, then re-immersed in liquid nitrogen for 5-10 seconds, squeezed and used Further; The direction of rolling the tampon during the cryoexposure on the same section of the skin surface was changed in the direction of the wrinkles (along the elastic fibers) and short movements perpendicular to them. Further, the same sites were treated with tampons with cells in 1/20 and then - in 1/30 of the circumference of the tampon. After 5 minutes, on the sites that had been subjected to cryo-exposure first, noticeable hyperemia appeared in the form of oblong stains. Subsequent cryotherapy was performed where hyperemia was less pronounced or had not yet occurred. Hyperemic sites were then re-treated up to 5 times with large tampons with different cells.

Next, a tampon with large (1/10 of the length of the circumference) cells and a diameter of 1/3 of the length of the eye slit was treated in the skin in the brow region, near the nose, in the parotid and near-humeral areas, at the outer nose, with a swab with large cells and a diameter of 1 / 5 of the eye gap - the skin near the wings of the nose, at the nostrils, on the eyelids, in the region of the inner and lateral corner of the eye; A tampon with large cells and a diameter of 1/5 of the eye slit acted along the direction of the most pronounced wrinkles on the skin, with the other hand pulling the skin in a direction perpendicular to the tampon rolling line until the formation of a relief-check freezing zone on the wrinkle "bottom". Repeated the effects on the same sites with tampons of the same diameters, but with smaller cells, 3 times.

Further on, the hyperemic skin was repeated 2 times with cryoapplications corresponding in size to tampons with cells of different sizes, while the swelling rate of the tampon was somewhat reduced. Three times repeated the freezing of nevi in ​​the superciliary area and papillomas on the neck. The cryotherapy session was continued for 50 minutes.

On healthy hyperemic skin was repaired gel-balm, on edemas of nevi - antiseptic ointment. After an hour, after removing the gel, there was a disappearance of hyperemia, smoothing of fine wrinkles, purification of the pores, the skin clearly acquired a more healthy and fresh appearance. On the 2nd day after the procedure, the swelling of the pathological formations that underwent cryodestruction disappeared, after 2 weeks the cryonecrotic tissues were torn away, in a month the redness in places of tissue rejection and the existing pigment changes almost completely disappeared. Cryotherapy was repeated after 1 month. A pronounced rejuvenating and healing effect of the procedure was noted. There are no complications and complaints from the patient.

CLAIM

A method of cryogenic treatment of the skin, including preliminary treatment of the skin and direct exposure to the skin with a tampon moistened in liquid nitrogen, characterized in that the skin is treated with alcohol-free cleansing and moisturizing agents before treatment, treatment begins with cryodestruction of pathological foci and pigment changes, 3 trial applications, using a tampon with a characteristic relief pattern of the surface, select the optimal exposure mode for cryoexposure for the appearance and disappearance of a characteristic pattern of the tampon for 1-3 seconds on the white surface of the skin, the treatment is performed first on the most open, and then on less accessible Areas of the skin surface, using alternately sets of tampons of different diameters and with different values ​​of the relief pattern, each applicator is operated continuously for 2-5 seconds, the procedure with each applicator is repeated 3-5 times, after the appearance of uniform hyperemia of cryoexposure is repeated in the same sequence, The session is continued for 40 minutes - 1 hour, at the end of the session the skin is treated differentially with nutrients and medicines, the treatment is repeated after 1-3 months.

print version
Date of publication 01.04.2007гг