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INVENTION
Russian Federation Patent RU2098148
METHOD FOR THE TREATMENT OF PSORIASIS
Name of the inventor: Tereshin KY
The name of the patentee: Khabarovsk State Medical Institute
Address for correspondence:
Starting date of the patent: 1994.11.15
The invention relates to a dermatology, to improve therapeutic efficacy torpid treating psoriasis. SUMMARY OF THE INVENTION Heparin is administered topically and fibrinolysin by electrophoresis.
DESCRIPTION OF THE INVENTION
The invention relates to medicine, in particular for dermatology.
Known methods for treating psoriasis, which employ quartz, ointments, vitamins, subcutaneous administration of heparin. But these methods are a little help in the treatment of torpid forms of psoriasis: palmar-plantar and arthropathic. In addition, administration of heparin subcutaneously in the abdominal region of hematoma causes pain, and the required control of blood clotting. remission period is not more than 6 months. Patients are often given disability group 2 without the right to work.
The purpose of the invention increase the therapeutic efficacy of treatment.
To achieve the objective act locally on the palms, soles or joints electrophoresis, and a negative electrode (cathode) is administered heparin. Heparin is not split into components and space reaches lesion intact. For better penetration of heparin and reduce inflammation dimexide added.
On the positive electrode is introduced fibrinolizin. Plasmin is required for resorption of fibrin adhesion and infiltration, resulting in the defeat of the ground, but also to normalize dissiminirovannogo intravascular coagulation. The course of treatment consists of 15-20 procedures. After 3-4 months, repeat the treatment. As a result, the treatment of lower disability group with 2 to 3 or do not allow the occurrence of disability.
The local administration of the heparin by electrophoresis with fibrinolizinom normalized intravascular coagulation in the lesion, so there is no need for constant monitoring of blood clotting.
The method is as follows:. 5-10 thousand IU of heparin sodium salt are dissolved in 25-30 ml of distilled water and the resulting solution was added 3-5 drops Dimexidum. Medicinal drug solution moistened disposable lining made of one or two layers of filter paper which is placed between the skin and the lining cloth hydrophilic. Plasmin of 2,000 IU (1 vial) diluted with distilled water, acidified with hydrochloric acid to pH 5,0 5,2. The resulting solution dosage moistened pad and, depending on the size of the lesion used in parallel arrangement transverse metal electrode area the same or different. For domestic use electrophoresis apparatus "Flow 1" AGBK-1, AGN-32, and others. The duration of the procedures for 15-20 minutes daily. The course of treatment consists of 15-20 procedures. After 3-4 months, repeat the treatment.
Example 1. Patient A. 35 years, the driver profession. He suffers from psoriasis for over 6 years. The last 2 years there was defeat in the palms and soles, are not amenable to conventional methods of psoriasis therapy and is not permitted even in the summer under the influence of sunlight. Due to the presence of fractures, pain, dysfunction of brushes (compression "donut" at the helm of the truck driver), long-term presence in the outpatient and inpatient treatment, the lack of prospects in the resolution process of the skin the patient has been issued 2 group disability.
Appointed electrophoresis of heparin and fibrinolizina Dimexidum with the addition of 20 minutes daily on the palmar and plantar surfaces. After 20 treatments the patient's pain disappeared, zaepitelizirovalis cracks, significantly reduced infiltration (thickening) of the skin in the lesions, fingers began to shrink into a fist.
After repeated course of electrophoresis in 3 months the patient was transferred to the 3 group disability, and then work with the right car mechanic.
Example 2. Patient M. 45 years. Diagnosis: artropaticheskom (defeat of the joints of fingers).
The patient were treated by electrophoresis with the combined administration of heparin and fibrinolizina adding Dimexidum. A 15 procedures for 15-20 minutes, for a course of 20 sessions electrophoresis. In the treatment of a gradual easing of pain in the joints, first alone, then with the movement (walking and compression of the fingers into a fist). A second course was held 3 months, against which the function of the joints is almost normal.
CLAIM
A method of treating psoriasis comprising administering heparin, wherein the heparin is administered topically by electrophoresis from the cathode, the anode administered simultaneously with fibrinolysin.
print version
Publication date 01.04.2007gg
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