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INVENTION
Russian Federation Patent RU2193412
Biologically active preparations, MANAGING ontogenesis
BIOLOGICAL OBJECT
Name of the inventor: Isaev, NN
The name of the patentee: Closed Joint Stock Company "SKY LTD"
Address for correspondence: 105554, Moscow, ul. Day, 66, kv.135, pat.pov. T.K.Shirokovoy
Starting date of the patent: 1999.09.27
The invention relates to Gerontology, namely vegetable means controlling the ontogeny of a biological object, and can be used in medicine, animal husbandry, agriculture. As a biologically active drug, a biological object manager ontogeny, used homeopathic solution first decimal dilution of the mixture of juices families pea sprouts "lequminosae" and "Pisum sativum" and juice sage leaves "Salvia officinalis". The drug is an effective and affordable vegetable biologically active agent, allowing work on the object, depending on the specified requirements, ie two or more times to slow cell growth, or to maintain an object in a constant state of, or preventing the growth of new formations.
DESCRIPTION OF THE INVENTION
The invention relates to Gerontology, namely vegetable means controlling the ontogeny of a biological object, and can be used in medicine, animal husbandry, agriculture.
Known medicinal herbal remedy derived from the ginseng root, which increases the lifespan of the experimental animals (Chebotarev DF "Drug therapy in the elderly and old age" materials Union Conference, Kiev, 1968, p. 94).
It is known that as the active drug control ontogeny biological object, use the extract of the roots plants perestupnya white (Bryonia alba L.) (RF patent 2087153 for cl. A 61 K 35/78, 1992).
However, the known bioactive agents have a number of drawbacks:
- low yield of plant material,
- difficulties with the cultivation of cultivated plants,
- relatively low efficiency - an increase of 10-36% survival of experimental animals (animal life from the beginning of the experiment)
- all known and used previously biologically active agents do not allow to leave the state of the biological object unchanged since the beginning of the application or delay the change of state.
An object of the present invention is to search for more effective and affordable vegetable biologically active drug, allowing work on the object, depending on the specified requirements, TE 2 or more times to slow cell growth, or to maintain an object in a constant state of, or preventing the growth of new formations.
The technical result of the proposed decision is achieved by creating a biologically active drug control ontogeny of a biological object, formed on the basis of medicinal plant resources, which according to the invention as the herbal remedies used homeopathic solution first decimal dilution juices of seedlings of different varieties of peas, one of which is grown in the greenhouse in diffuse light, and the other - in a dark closet in wet sawdust, and sage leaves drug juice, grown in open beds and collected during its flowering. The invention is characterized by the fact that the use of pea seedlings family "Lequminosae" and "Pisum sativum", varieties of "Winner of the G-33" and "May 13", the use of pea seedlings family "Lequminosae", grown at a temperature of 22-24 o C. and the age of 12-14 days, and the family "Pisum sativum" - at a temperature of 22-25 o C and 14-14.5 days before.
The invention is also characterized in that the leaf juice of sage varieties of "Salvia officinalis"
As a result of the experiments it found that the biologically active agent with desired characteristics is obtained only from said plant components obtained within a specified time and within the (temperature, age and plants growing medium) and only at a certain homeopathic their solution.
If the parameters of any of the plant components are outside the specified limits, the necessary characteristics will not be achieved, ie. E. The technical result is obtained in the invention.
This suggests that components of these parameters are essential features of this invention.
The technical result is achieved in the present invention when any ratio of the ingredients.
Proposed biologically active drug, the biological object manager ontogeny, are prepared as follows.
Please separately prepare juices of pea seedlings families "Lequminosae" and "Pisum sativum" and juice leaves sage "Salvia officinalis"
Moreover pea seedlings family "Lequminosae" are grown in the greenhouse at a temperature of 22-24 o C in diffuse light for 12-14 days, and the family of pea seedlings "Pisum sativum", such as, for example, grades "Winner G-33" and " May -13 "are grown in a dark closet in wet sawdust at a temperature of 22-25 o C.
Salvia officinalis "Salvia officinalis" is grown in open beds and leaves collected during flowering.
Then, the collected from each plant individually squeeze the juice. Mix juices together and defend this mixture in a dark place, and then make the first decimal homeopathic dilution.
Specific modes of preparation of this drug that are not listed in the description are known, they do not constitute the subject of patent protection and are therefore not disclosed in the application materials.
Prepared biologically active drug can be used directly as a solution or homeopathic device for using energy-transfer properties of drugs "Transfer-P" to move it on media properties. (Center for Intelligent Medical Systems "IMEDIS." "User's Guide to the appliance for the energy-transfer properties of drugs" Shuttle-U. "Moscow, 1994, p. 3.5-8).
As carriers solid, liquid or gaseous substances can be used, such as water, alcohol, saline, sugar, homeopathic grit etc.
Impacts on biological object can be either external or internal.
After transfer of information in the medium it is used to influence the biological object.
Biological objects can be people, animals, birds, etc.
Proposed a biologically active drug, Managing ontogeny of a biological object, it has been tested. The most visible results of the proposed product are listed below.
1. Work carried out in the vivarium CSRL TSOLIU doctors to breed rabbits "Dutchman."
In the period from 08.07.99 till 22.08.99, the female (weight 3,055 kg) and male (weight 3,630 kg) rock "Dutchman" contained in the filtered water, which was recorded information with a biologically active drug, a biological object manager ontogeny made in the form of a homeopathic dilution solution first decimal juice mixture pea seedling families "Lequminosae" and "Pisum sativum" and medicinal sage leaf juice "Salvia officinalis".
Mating was carried out in the period from 26.07.99 on 28.07.99. After 37 days after mating was not only labor but the body weight was observed even slightly less than at the beginning of the experiment (at 3,005 and 3,605 females in the male).
Normal gestation in rabbits above is from 28 to 32 days.
2. testing of biologically active preparation has been carried out, the control of the biological object ontogeny applied against the development of peritonitis in rabbits.
The work was conducted in the Central Research Laboratory vivarium TsOLIUvrachey to breed rabbits "Chinchilla". The weight of the test group rabbit 1 was 1,995 kg, and rabbit 2 - 1,520 kg.
All of them were kept in filtered water (used as carrier), which moved energoinformatsii proposed homeopathic solution with the device "Shuttle-U".
rabbits The regime was as follows.
Alternately day water obtained by the device "-P Transfer" day - crude tap water and so on until the end of the experiment.
In the middle of the experience of the rabbits of the experimental group entered a microbial association of the following composition in a concentration of 10 3: streptokkok, Pseudomonas aeruginosa, Proteus.
The next day, an external examination showed sluggish, as if sleepy condition of the animals and almost no natural eyes shine. Then the rabbits of the experimental group had normal mobility and the eyes shine.
In the control group died from peritonitis on 3-4 day from the moment you enter the microbial associations of the above.
3. The testing of biologically active preparation was carried out controlling ontogeny of the biological object to be used for the treatment of melanoma in laboratory mice.
The work was conducted at the Institute of General Genetics, Vavilov.
For handling objects as experimental mouse lines were taken S057 "Black", female. This line is characterized by a predisposition to the development of melanoma.
In the experimental and control groups were five animals. The mice were housed in plastic cages with metal bars.
In order to avoid energy-information exchange between groups of cells from mice were removed from each other as far as possible. In the cell with the control group of mice was established grounding.
They fed mice a dry forage and grain fed water.
From each group were selected and marked by three mice. The animals were measured daily body weight. In the absence of any effects of daily fluctuations in body weight in mice was 0.7 g
Mice entered murine melanoma cells B-16, diluted in standard medium KRMU-1640 supplemented with 10% fetal cattle serum. Intramuscular injection was carried out in the right thigh at the rate of 100 thousand. Melanoma cells per mouse.
Simultaneously, on a cell with the experimental group mice mounted hermetically closed bottle with water containing information received from the drug proposed by this invention. By means of the foil from the information transmitted in a bottle of water in the water, which is fed mice.
The bottle with the carrier was replaced with a new one every two weeks. Continued daily weigh mice previously marked.
In the experimental group, the daily fluctuations in body weight in mice increased. The maximum difference in weight per day was 2.9 g
17 days after injection of melanoma cells in mice began to appear on the hip of the tumor. Tumor growth in the average in the control mice was more intense than in mice involved in the experiment. After some time, the mice of the experimental group did not have tumors.
It should be noted that it is observed in these mice largest daily fluctuations in body weight.
Then the mouse began to die. Within weeks, all mice died in the control group. Moreover, the average life expectancy of the mice in the experimental group was 3 days longer than the control group.
Given the rapid development of the tumor, this figure is very significant.
At autopsy revealed that the cause of death of mice was the primary tumor, melanoma, arising in the injection of melanoma cells. It caused severe intoxication, in some cases, intestinal obstruction. there was virtually no metastasis.
Mice of the experimental group were killed for histological analysis. When viewing preparations melanoma cells were detected.
From the foregoing, it must be concluded that the biologically active drug are changed, the control ontogeny of a biological object, can prolong the life of tumor-bearing animal, and if possible to achieve significant fluctuations in body weight due to the correct dosage of the media, and to prevent the development of tumors.
CLAIM
Biologically active drug control ontogeny biological object made of medicinal herbal remedies, characterized in that the herbal remedies using homeopathic solution first decimal dilution juices from seedlings of different varieties of peas, one of which was grown in a greenhouse in diffuse light, and the other - in a dark closet in wet sawdust, and sage leaves drug juice, grown in open beds and collected during its flowering.
Biologically active drug control ontogeny biological object according to Claim. 1, characterized in that the seedlings of peas "Leqiminosae" and "Pisum sativum".
Biological active preparation, managing ontogeny biological object according to claim. 2, characterized in that the family of peas "Pisum sativum", grades such "Winner G-33" and "May 13".
Biologically active drug control ontogeny biological object according to claim 1, characterized in that the family of pea seedlings "Leqiminosae", grown at a temperature of 22-24 o C, and family "Pisum sativum" -. At a temperature of 22-25 o C.
Biologically active drug control ontogeny biological object according to Claim. 1, characterized in that the sage leaf juice grades "Salvia officinalis".
Biologically active drug control ontogeny biological object according to Claim. 1, characterized in that the family of pea seedlings "Leqiminosae" age 12-14 days, a "Pisum sativum" -14-14,5 day.
print version
Publication date 13.12.2006gg
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