poisons
- Substances which, acting chemically or physico-chemically and introduced into the body in relatively small amounts, under certain conditions, cause health disorder or death.
Action Ya on the body depends on:
1) from the Ya - number, solubility, physical condition, J., synergism, concentration, storage time and stability Ya;
2) by the human body - the age, health, weight, sex addiction;
3) J. of routes of administration - the mouth, respiratory tract, rectum, vagina, by administration under the skin.
Classification I .:
1) poisons that cause tissue damage in the area of impact - local (caustic);
2) poisons that exhibit toxic effects on the body when they are sucking the blood, -rezorbtivnye;
3) food poisons (food poisoning, mycotoxicoses).
Resorptive Ya depending on the mechanism of action cause certain clinical and morphological manifestations.
Types rezorbtivnyhYa .:
1) destructive, causing changes in the cells of internal organs, disrupting their structure and function with the development of dystrophy, -Mineral Ya, heavy metal salts, mercuric chloride and arsenic compounds;
2) blood - carbon monoxide bertoletova salt, nitrates, nitrites, nitrobenzene, snake venoms;
3) functionalities that do not cause morphological changes in the internal organs, but accompanied by a disturbance of enzymatic systems and cell functions of various internal organs:
a) heart - cardiac glycosides;
b) neurotropic - hypnotics, narcotics, stimulants, anti-depressants;
c) obschefunktsionalnye - hydrocyanic acid and its derivatives.
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