Medication Description: Mazindol (Mazindol)
MAZINDOL (Mazindol) *. 5- (4-Chlorophenyl) -2, 5-dihydro-3H-imidazole- [2, 1-a] -isoindol-5-ol.
Synonyms: Terenac, Teronak, Afilan, Dimagrir, Magrilan, Samonter, Sanorex, Terenac.
The chemical structure differs from phepranon and dezopimon, but is similar in action to them. It has anorexigenic effect. Facilitates adherence to a low-calorie diet.
The main factors in the mechanism of anorexigenic action of mazindol are also an increase in the activity of the saturation center in the hypothalamus and a decrease in stimuli for the need for food, which is associated with the effect of the drug on the adrenergic systems of the brain.
Mazindole also has a moderate antidepressant effect.
Applied in the complex treatment of obesity in adults and children over 12 years. Assign inside with meals at the beginning, 1/2 tablet (0.5 mg) per day (for the first 4 to 5 days), then 1 tablet 1 or 2 times a day (during breakfast and lunch). The maximum daily dose of 3 tablets. The course of treatment usually lasts from 4 to 12 weeks.
When taking the drug may dry mouth, nausea, headache, sleep disorders, urinary retention, sweating, allergic skin rash, increased blood pressure. The dose of the drug in these cases, reduce or stop taking it. In the course of treatment (at the 8th - 10th week), some addiction to the drug and a decrease in its anorexigenic effect may develop.
The drug is contraindicated in glaucoma, kidney, liver and heart failure, cardiac arrhythmias, increased excitability. You should not appoint mazindol concurrently with MAO inhibitors (see Nialamide).
Product form: 1 mg tablets in a package of 20 and 100 pieces.
Storage: List A. Released only by prescription.