Description of the medicine: Mazindol (Mazindol)
MAZINDOL (Mazindol) *. 5- (4-Chlorophenyl) -2, 5-dihydro-3H-imidazole- [2, 1-a] -isoindol-5-ol.
Synonyms: Terenak, Teronak, Afilan, Dimagrir, Magrilan, Samonter, Sanorex, Terenac.
In chemical structure it differs from fepranon and desopimon, but in action it is close to them. It has anorexigenic effect. Facilitates a low-calorie diet.
The main factors in the mechanism of the anorexigenic effect of mazindole are also an increase in the activity of the saturation center in the hypothalamus and a decrease in incentives for food demand, which is associated with the effect of the drug on the adrenergic systems of the brain.
Mazindol is also characterized by a moderate antidepressant effect.
Used in the treatment of obesity in adults and children over 12 years old. Assign inside with food, first 1/2 tablet (0.5 mg) per day (in the first 4 to 5 days), then 1 tablet 1 or 2 times a day (during breakfast and lunch). The maximum daily dose is 3 tablets. The course of treatment usually lasts from 4 to 12 weeks.
When taking the drug, dry mouth, nausea, headache, sleep disturbances, urinary retention, sweating, allergic skin rash, and high blood pressure are possible. The dose of the drug in these cases is reduced or discontinued. In the process of treatment (at 8-10 weeks), some addiction to the drug and a decrease in its anorexigenic effect may develop.
The drug is contraindicated in glaucoma, renal, liver and heart failure, cardiac arrhythmias, increased irritability. Mazindol should not be prescribed simultaneously with MAO inhibitors (see Nialamide).
Release form: 1 mg tablets in a package of 20 and 100 pieces.
Storage: List A. It is released only by prescription.