Description of the medicine: Indigocarmin for injection (Indigocarminum pro injectionibus)
INDIGOCARMINE FOR INJECTION (Indigocarminum pro injectionibus).
Indigo-5, 5-bis-sulfonate sodium.
Dark blue powder. Soluble in 100 parts of water to form a deep blue solution.
It is used as a ready-made 0.4% solution in ampoules (pH 4, 0 - 5, 5) to study the excretory function of the kidneys and the dynamic activity of the renal pelvis and ureter (chromocystoscopic test, see also Methylene blue).
The use of indigo carmine is based on the ability of this dye to quickly excrete unchanged in the urine without causing impaired renal function.
The drug is administered as a 0.4% aqueous solution into a vein. Enter slowly. Before the introduction, the solution is heated to body temperature. Dose for adults - from 5 to 20 ml, for children - from 1 to 3 ml.
If it is not possible to inject a solution of indigo carmine into a vein, it is injected into the muscles in an amount of 20 ml.
The release of indigo carmine is monitored with a cystoscope; if one-sided kidney damage is suspected, ureteral catheterization is performed.
With normal kidney function, the paint after intravenous administration begins to stand out from the ureters after 2 - 3 minutes, staining the urine in blue. Maximum excretion is noted after 6 - 8 minutes. After another 3-5 minutes, the urine dye content sharply decreases, since by this time the main amount of the administered indigo carmine has time to stand out by the kidneys; complete isolation ends after approximately 90 minutes.
In patients with impaired renal excretory function, indigo carmine excretion occurs at a later date, less intensively, longer.
Slowing the release of indigo carmine is possible not only for kidney diseases, but also for decompensation of cardiac activity, hypertension and other diseases accompanied by impaired renal blood flow.
A solution of indigo carmine can also be introduced into the cavity and fistula to detect violations of the integrity of the cavity and the length of the fistulous passages. For this purpose, use a 0.4% solution or dilute 5 ml (1 ampoule) of the solution in 400 ml of isotonic sodium chloride solution.
Release form: 0.4% solution in ampoules of 5 ml in a package of 10 ampoules.
Storage: in the dark place.