Description of the medicine: Bromazepam (Bromazepam)
7-Bromo-1,2-dihydro-5- (2-pyridyl) -2H-1,4-benzodiazepine-2one.
Synonyms: Bromazepam, Bromidem, Kalmepam, Lexilium, Normok, Anxio-Puren, Bartul, Bromazep, Bromidem, Calmepam, Deptran, Lexilium, Lexotan, Lexotanil, Neurozepam, Normoc, Nulastres, Pascalium, etc.
By structure, action and indications for use, it is close to sibazon and other benzodiazepine tranquilizers.
After oral administration, it is absorbed quickly and completely, bioavailability is about 84%; Сmax - 1-2 hours; T1 / 2 - 10-12 hours; undergoes biotransformation in the liver, excreted by the kidneys mainly in the form of conjugated metabolites.
Take 0.0015-0.003 g (1.5-3 mg) and in a hospital - 0.006-0.012 (6-12 mg) 2-3 times a day.
Side effects are possible: dyspepsia, drowsiness, weakness, impaired concentration, memory impairment, hallucinations, ataxia, muscle weakness, arterial hypotension, decreased libido, impaired blood picture, etc.
Antipsychotics, other tranquilizers, antidepressants, sleeping pills, analgesics, anesthetics and alcohol enhance the effects of bromazepam.
Release form: tablets on 0,0015; 0.003 and 0.006 g (1.5; 3 and 6 mg) (N. 10).