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Medication Description: Buscopan

BUSKOPAN (Buscopan).
N-butylscopolamine or (1S, 3S, 5R, 6R, 7R, 8S) -epoxy-8-butyl-3 - / (S) -tropyl-oxy / tropane bromide.

Synonyms of butylbromide, hyoscina, Spasmalexin, Tirantil, Toscopan.

White crystalline powder. Easily soluble in water.

Semi-synthetic hyoscyamine derivative.

It has a pronounced selective m-cholinolytic effect. Like other quaternary ammonium compounds, it is poorly absorbed in the gastrointestinal tract, does not penetrate the blood-brain barrier.

Effective with spasms of smooth muscle organs, in some cases superior to no-silo and papaverine.

Used to treat spastic pain conditions with cholelithiasis and urolithiasis, chronic cholecystitis, gipermotornaya esophageal dyskinesia, gallbladder and biliary tract, gastric ulcer and duodenal ulcers, irritable bowel syndrome, dysmenorrhea, and for late disclosure of uterine throat during birth, with pylorus in infants.

Used for X-ray studies of the gastrointestinal tract, if necessary, to reduce the tone and peristalsis of the stomach and intestines.

Apply inside, rectally and parenterally.

Inside take 0.01-0.02 g (10-20 mg) 3-5 times a day with a glass of water.

Rectally prescribed for adults and children (over 6 years old) with 1-2 suppositories 3-5 times a day.

For acute attacks of spastic pain, subcutaneously, intramuscularly or intravenously, 0.02 g (the contents of 1 ampoule) is injected 1-2 times a day.

Buscopan is usually well tolerated. Anticholinergic adverse reactions (dry mouth, tachycardia, urinary retention) are rare, they are less pronounced than with atropine, and go away on their own.

The drug is contraindicated in glaucoma and prostatic hypertrophy.

Method of issuance: Bean to 0.01 g (N. 10); rectal suppositories of 0.01 g (N. 5); 2% solution in 1 ml ampoules.