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Description of the medicine: Buscopan (Buscopan)

BUSCOPAN (Buscopan).
N-Butylscopolamine or (1S, 3S, 5R, 6R, 7R, 8S) -epoxy-8-butyl-3 - / (S) -tropyl-hydroxy / tropane bromide.

Synonyms: Butylscopolamine bromide, Hyoscine butylbromide, Hyoscin-N-butylbromide, Spanil, Alcopan Amisepan, Antispaspin, Brobutil, Buscol, Buscolamin, Buscolysin, Buscopin, Buscoridin, Butylscopolambromomomyl Butylomomylomyl, Butylscomidomyl, Butylscomomom, Butomidomyl, Butylscomomom, Butomidomyl, Butylscomilomom, Butomidomyl, Butylscopol Spasmalexin, Tirantil, Toscopan.

White crystalline powder. Easily soluble in water.

Semi-synthetic derivative of hyoscyamine.

It has a pronounced selective m-anticholinergic effect. Like other quaternary ammonium compounds, it is poorly absorbed in the digestive tract, does not penetrate the blood-brain barrier.

Effective for spasms of smooth muscle organs, in some cases it surpasses no-shpu and papaverine.

It is used to treat spastic pain conditions in gallstone and urolithiasis, chronic cholecystitis, hypermotor dyskinesia of the esophagus, gall bladder and biliary tract, with peptic ulcer of the stomach and duodenum, irritable bowel syndrome, dysmenorrhea, and also with late opening of the uterus during labor with pylorospasm in infants.

They are also used for X-ray examination of the gastrointestinal tract, if necessary, to reduce the tone and motility of the stomach and intestines.

Apply orally, rectally and parenterally.

Inside take 0.01-0.02 g (10-20 mg) 3-5 times a day, washed down with water.

Rectally prescribed for adults and children (over 6 years), 1-2 suppositories 3-5 times a day.

In acute attacks of spastic pain, 0.02 g (contents of 1 ampoule) is administered subcutaneously, intramuscularly or intravenously 1-2 times a day.

Buscopan is usually well tolerated. Anticholinergic adverse reactions (dry mouth, tachycardia, urinary retention) are rare, they are less pronounced than with atropine, and pass on their own.

The drug is contraindicated in glaucoma and prostatic hypertrophy.

Method of release: dragee of 0.01 g (N. 10); rectal suppositories of 0.01 g (N. 5); 2% solution in ampoules of 1 ml.