Description of the medicine: Calcitriol (Calcitriol)
(1α, 3β, 5Z, 7E) -9,10-Secocholest-5,7,10- (19) triene-1,3,25-triol.
Synonym: Rockaltrol, Rocaltrol.
White crystalline powder. Relatively soluble in water, soluble in organic solvents.
A synthetic analogue of the active metabolite of vitamin D (cholecalciferol).
Promotes the absorption of calcium in the intestines, regulates bone mineralization, stimulates osteoclasts.
It is used for rickets, menopausal osteoporosis, as well as for osteodystrophy of the renal origin (with renal failure, including hemodialysis) and hypoparathyroidism (postoperative and idiopathic).
It is prescribed orally for adults, starting from 0.25 μg per day, if necessary, the daily dose is increased within 2-4 weeks by 0.25 mg to 0.5-1 mg and higher: for menopausal osteoporosis, 0.25 μg is used 2 times in a day.
Children are prescribed 0.01-0.1 μg / kg.
Possible side effects: hypercalcemia, headache, vomiting, constipation, upset sensation, fever, thirst, polyuria, dehydration, apathy, stunted growth, urinary tract infection.
The drug is contraindicated in hypercalcemia.
After 1, 3 and 6 months, and then with an interval of 6 months, it is necessary to determine the calcium content in the blood.
Release form: capsules of 0.25 and 0.5 μg (N. 30, 100).
Storage: List B.