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Medication Description: Calcitriol (Calcitriol)

Calcitriol (Calcitriol).

(1α, 3β, 5Z, 7E) -9,10-Secoholesta-5,7,10- (19) triene-1,3,25-triol.

Synonym: Rocaltrol, Rocaltrol.

White crystalline powder. Relatively soluble in water, soluble in organic solvents.

Synthetic analogue of the active metabolite of vitamin D (cholecalciferol).

Promotes calcium absorption in the intestine, regulates bone mineralization, stimulates osteoclasts.

Applied with rickets, menopausal osteoporosis, as well as with osteodystrophy of renal origin (with renal failure, including on the background of hemodialysis) and hypoparathyroidism (postoperative and idiopathic).

Assign inside adults, starting with 0.25 mg per day, if necessary, increase the daily dose for 2-4 weeks by 0.25 mg to 0.5-1 mg and above: for menopausal osteoporosis, use 0.25 mg 2 times in a day.

Children are prescribed at 0.01-0.1 mg / kg.

Possible side effects: hypercalcemia, headache, vomiting, constipation, sensitivity disorder, fever, thirst, polyuria, dehydration, apathy, growth retardation, infection of the urinary tract.

The drug is contraindicated in hypercalcemia.

After 1, 3 and 6 months, and then with an interval of 6 months it is necessary to determine the content of calcium in the blood.

Form release: capsules of 0.25 and 0.5 μg (N. 30, 100).

Storage: List B.