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Description of the medicine: Sibutramine (Sibutramine)
SIBUTRAMINE (Sibutramine).
(±) - (n-Chlorophenyl) -α-isobutyl-N, N-dimethylcyclobutanomethylamine hydrochloride.
Synonym: Meridia, Meridia.
The chemical structure is similar to fluoxetine and, like it, has an antidepressant effect. Like fluoxetine, it is an active inhibitor of serotonin reuptake. However, it actively inhibits the reuptake of norepinephrine. Abroad used as an antidepressant. At the same time, studies conducted abroad and in a number of medical institutions in Russia show that sibutramine has a pronounced anorexigenic activity. A significant part of patients (including those suffering from diabetes mellitus) taking it against the background of a low-calorie diet showed a decrease in body weight (within 3 months) by 5-10%.
Assign inside of 0.005 g (5 mg) 2-3 times a day.
Sibutramine is generally well tolerated. Despite the inhibition of the capture of norepinephrine, it does not have a pronounced sympathomimetic (and therefore hypertensive) effect (monitoring blood pressure, however, is necessary!); possible constipation, insomnia, excessive loss of appetite.
Release form: capsules of 0.01 and 0.015 g (10 and 15 mg).
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