Description of the medicine: Terbutalin (Terbutalin)
TERBUTALIN (Terbutalin) *. 1- (3, 5-dioxiphenyl) -2- (tert-butylamino) ethanol.
Synonyms: Brikanil, Arubendol, Asthmasian, Betasmac, Bricalin, Brican, Bricanyl, Bricar, Dracanyl, Spiranyl, Terbasmin, Terbutol, Tergil, etc.
In chemical structure and pharmacological properties it is close to salbutamol. It has a bronchodilator and tocolytic effect.
As a bronchodilator, it is used in the form of an aerosol and tablets. Adults are prescribed 1 to 2 tablets (2, 5 mg) 1 to 2 - 3 times a day. Children aged 3 to 7 years - 1/4 - 1/2 tablets, from 7 to 15 years - 1/2 tablet 2-3 times a day. In bronchial asthma, sometimes they begin with the introduction of 1/2 ampoules (0.25 mg) no more than 3 times a day (adult) under the skin.
There is evidence of the successful use of terbutaline in the form of an aerosol in chronic obstructive pulmonary diseases in patients with myocardial infarction. Along with the improvement of alveolar ventilation, an increase in left ventricular myocardial contractility and an improvement in hemodynamic parameters were noted.
As a tocolytic agent (in obstetric practice), they are used in the form of drip intravenous infusions (10 - 25 μg per minute in an isotonic solution of glucose or sodium chloride) with a further transition to subcutaneous injection (250 μg = 1/2 ampoule) 4 times a 3 days a day. At the same time, 5 mg is prescribed orally 3 times a day.
Possible side effects and contraindications are the same as for other b-adrenostimulants.
Method of release: in aerosol containers; tablets of 0.0025 g (2.5 mg) in a package of 20 pieces; 0.05% solution (0.5 mg) of terbutaline sulfate in ampoules containing 1 ml, in a package of 10 ampoules.
Storage: List B.