Medication Description: Cineepres (Sinepres)
Combined tablets containing dihydroergotoxin methanesulfonate 0.0006 g (0.6 mg), reserpine 0.0001 g (0.1 mg), hydrochlorothiazide 0.01 g (10 mg). Covered in purple-pink color (Tabulettae "Sinepres obductae").
The dihydroergotoxin methanesulfonate contained in the tablets, i.e., Rodergin (see), has a a-adreno-blocking effect, reperpine (see) has a sympatolytic effect, hydrochlorothiazide (see) is a powerful diuretic agent.
In the aggregate, the drug has a positive effect in hypertension. Selected doses are calculated on the effectiveness of the drug and good tolerance in mild and moderate arterial hypertension.
Assign inside (after eating) 1 tablet 2 times (3 times) per day. After achieving a therapeutic effect, the dose is reduced to 1 tablet per day. The treatment is carried out for a long time. Due to the fact that with prolonged use it is possible to develop hypokalemia (due to the content of hydrochlorothiazide), it is necessary to prescribe a diet rich in potassium, and to control the content of potassium in blood serum.
With the use of sinepresa possible deterioration of mood, weakness, drowsiness, nasal congestion. Considering the peculiarity of its effect on the central nervous system, the content of reserpine in the preparation, one should not prescribe synepress to patients prone to depression. Persons whose work requires increased attention (operators, drivers of transport, etc.) should not receive a sinapress before and during work.
The drug is contraindicated in violation of the functions of the liver and kidneys, during pregnancy and breastfeeding.
Form release: tablets (total weight with fillers 0.1 g) in a package of 10 and 50 pieces.
Storage: List B. In a dry, dark place.