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Description of the medicine: Cyproheptadine (Cyproheptadinum)

Cyproheptadine (Cyproheptadinum) *. 4- (5-Dibenzo [a, d] cycloheptatrienylidene) -1-methylpiperidine hydrochloride.

Synonyms: Peritol, Adekin, Apetigen, Astonin, Cipractin, Cyprodin, Cyproheptadin hydrochlorid, Istabin, Pariactin, Peritol, Supersan, Vieldrin, Vinorex, etc.

Cyproheptadine has anti-histamine activity (blocks H 1 receptors), but at the same time it is a strong anti-serotonin substance (it reduces spasmogenic and other effects caused by serotonin). It also has anticholinergic activity. It has an anti-allergic effect, and is especially effective for itchy dermatoses (possibly due to antiserotonin action). The drug blocks somatotropin hypersecretion in acromegaly and ACTH secretion in Itsenko Cushing's syndrome.

It is used for allergic diseases (acute and chronic urticaria, serum sickness, pollinah, vasomotor rhinitis, contact dermatitis, neurodermatitis, Quincke's edema, allergic reactions to medications, etc.), as well as for migraines (mainly due to the antiserotonin effect) , with loss of appetite of various etiologies (neurogenic anorexia, chronic diseases, etc.).

Due to the fact that histamine and serotonin enhance the secretion of pancreatic juice, it is also proposed to use cyproheptadine in the treatment of chronic pancreatitis.

Assign inside: adults 4 mg (1 tablet) 3-4 times a day, children in smaller doses in accordance with age. At the age of 6 months to 2 years, it is prescribed with caution in a daily dose of up to 0.4 mg / kg; from 2 to 6 years - up to 6 mg per day (1/2 tablet 3 times a day); from 6 to 14 years - up to 12 mg per day (1 tablet 3 times a day). Daily doses should not exceed 32 mg in adults, 8 mg in children 2–6 years old, 12 mg in 6–14 years old.

When using the drug, drowsiness, dry mouth are possible, in rare cases - anxiety, ataxia, dizziness, nausea, skin rash.

Given the pronounced sedative effect, caution should be exercised when prescribing the drug to persons whose work is associated with intense physical and mental activity. During treatment with the drug can not drink alcohol.

The drug is contraindicated in pregnancy, glaucoma, urinary retention, predisposition to edema.

Method of release: 4 mg tablets in a package of 20 pieces; syrup (for children) in 100 ml vials (in 1 ml 0.4 mg of the drug).

Storage: List B.