Description of the medicine: Foridon (Foridonum)
FORIDON (Foridonum). 2, 6-Dimethyl-3, 5-dimethoxycarbonyl-4- (2-difluoromethoxyphenyl) -1, 4-dihydropyridine.
Synonyms: Riodipin, Riosedil, Riodipin, Riosedyl.
White crystalline powder with a greenish tint. Almost insoluble in water, soluble in alcohol.
The chemical structure, pharmacological and therapeutic properties are close to nifedipine (phenygidine), which differs in that position 4 contains not nitrophenyl, but difluoromethoxyphenyl group.
It has a hypotensive, antispasmodic, coronary expansion effect.
Applied with hypertension of the I - II degree, angina pectoris.
Take orally (regardless of meal time) at a dose of 20-30 mg 3 times a day. The daily dose is up to 150 mg.
Foridotensive activity, foridon is slightly inferior to nifedipine [To achieve a therapeutic effect, foridon has to be prescribed in higher doses than nifedipine (phenigidine, corinfar). For hypotensive activity, 40 mg of foridon corresponds to 20 mg of nifedipine (Corinfar).].
The duration of treatment with foridone depends on the severity of the disease and can be many months. The initial therapeutic effect usually occurs at the end of the 1st week, persistent - after 2 to 3 weeks.
After taking foridon, redness of the skin of the face, headache, passing independently, are possible, 40-60 minutes after taking the medicine. Tachycardia may also develop, which occurs after a dose reduction or drug withdrawal.
Contraindications - see Phenigidin.
Release form: tablets of 0.01 g (10 mg) in a package of 40 pieces.
Storage: List B. In a dry, dark place.