Medication Description: Hydrocortisone (Hydrocortisonum)
Hydrocortisone (Hydrocortisonum). 17-Oxycorticosterone.
By chemical structure, hydrocortisone differs from cortisone by the presence of hydroxyl and a hydrogen atom instead of oxygen with a carbon atom in the C 11 position.
In medical practice, hydrocortisone (free alcohol), hydrocortisone acetate, hydrocortisone succinate (hemisuccinate) are used.
Synonyms of hydrocortisone: Cobadex, Cortef, Cortil, Cortisol, Genacort, Hydrocortal, Hydrocortone, etc.
Hydrocortisone is close to cortisone in its effects on the body, but is somewhat more active. The amount of the drug for ingestion and introduction into the muscles is 2/3 dose of cortisone.
Possible side effects, precautions and contraindications are the same as for cortisone.
Hydrocortisone (free alcohol) is rarely used orally. Used mainly for the manufacture of dosage forms.
Microcrystalline suspension of hydrocortisone (Suspensio Hydrocortisoni 25%)
Used for intraarticular (and periarticular) administration for arthritis of rheumatic and other origin (with the exception of purulent, tuberculous and gonorrheal), bursitis, tendovaginitis, etc.
5–25 mg (0.2–1 ml of suspension) are introduced into the joint cavity depending on the size of the joint and the severity of the lesion 1 time per week (up to 3–5 injections per course).
Product form: in vials of 5 ml suspension, containing 125 mg of hydrocortisone acetate. Before use, the contents of the bottle are thoroughly shaken.
Produced in Hungary.
Hydrocortisone ointment 1% (Unguentum hydrocortisoni 1%). Ointment yellowish white.
Applied with inflammatory and allergic skin diseases of non-microbial etiology: allergic and contact dermatitis, eczema, neurodermatitis, etc. Apply to the affected skin with a thin layer 2-3 times a day.
The use of the ointment is contraindicated in infectious skin diseases: tuberculosis, pyoderma, mycoses, as well as ulcerative lesions of the skin and wounds.
Form release: in aluminum tubes of 10 g.
Storage: in a cool dry place.
Hydrocortisone is part of the aerosol antibacterial drug << Oxicort>> (see).