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Medication Description: Alprazolam (Alprazolam)

ALPRAZOLAM (Alprazolam). 8-Chloro-1-methyl-6-phenyl-4H- [1, 2, 4] -triazolo [4, 3a] [1, 4] benzodiazepine.

Synonyms: Alprax, Xanax, Neurol, Alprax, Cassadan, Frontal, Neurol, Prinax, Restil, Solanax, Tafil, Trankimazin, Tricca, Xanax, Xanor, Zotran.

The chemical structure is close to triazolam (see), it is distinguished by the absence of a Cl atom with phenyl in position 6. Alprazolam has a less pronounced hypnotic effect. It is used mainly for short-term relief of anxiety, fear, anxiety, treatment of concomitant depression.

The drug is rapidly absorbed. Peak plasma concentrations are observed 1–2 hours after ingestion. The elimination half-life is 12–15 h. Frequent repeated use may, however, lead to cumulation, especially in cases of impaired renal and hepatic function in the elderly.

Assign inside adults in a dose of 0.25 - 0.5 mg (0.00025 - 0.0005 g) 3 times a day. The highest daily dose of 3 mg. Weakened and elderly patients are prescribed 0.25 mg 2 - 3 times a day; if necessary, and with good tolerability of the drug dose is gradually increased.

Possible complications, precautions and contraindications, see Chlosepid, Sibazon.

Product form: tablets of 0.25 mg white (ovate) and 0.5 mg yellowish-pink.