Description of the medicine: Calcium pangamate (Calcii pangamas)
CALCIUM PANGAMAT (Calcii pangamas).
Calcium salt of gluconic acid ester and dimethylglycine. (The drug also contains about 25% calcium gluconate and 6% sodium chloride.)
Synonyms: Vitamin B15, Calgam, Calgam.
White or white with a yellowish tint powder with a characteristic odor. Soluble in water, insoluble in alcohol. Hygroscopic.
According to reports, calcium pangamate has a beneficial effect on metabolism: improves lipid metabolism, increases oxygen uptake by tissues, increases the content of creatine phosphate in muscles and glycogen in muscles and liver, and eliminates the effects of hypoxia.
In the mechanism of action of calcium pangamate, perhaps, its ability to give active methyl groups plays a role (see also Choline chloride, Lipocaine, Methionine.). It should also take into account the value that calcium ions contained in the preparation (in significant quantities) can have.
It is used as one of the means of complex therapy for various forms of atherosclerosis, including chronic forms of coronary insufficiency, atherosclerosis of vessels of the lower extremities I and II stages, cerebral vascular sclerosis, etc., with emphysema and pneumosclerosis, chronic hepatitis, chronic alcohol intoxication, skin and venereal diseases (itchy dermatoses, syphilitic aortitis, etc.); It is also prescribed for better tolerance of sulfonamides, corticosteroids and other drugs.
Take orally in tablets (50 mg), 1 to 2 tablets 3-4 times a day. Daily doses: for adults, 100-300 mg; for children under 3 years old - 50 mg, from 3 to 7 years old - 100 mg, from 7 to 14 years old - 150 mg. Treatment is carried out in courses of 20 to 40 days with a repetition after a 2 to 3-month break.
The drug is usually well tolerated; caution must be exercised with a significant increase in blood pressure.
Release form: tablets on 0,05 g (50 mg), coated, in a package of 100 tablets.
Storage: in tightly sealed containers in a dry place at a temperature not exceeding +18 'C.