Description of the medicine: Fepromaron (Phepromaronum)
FEPROMARON (Phepromaronum). 3-a-phenyl-b-propionylethyl-4-hydroxycoumarin.
Odorless crystalline powder, white or white with a slightly creamy tint. It is practically insoluble in water, slightly soluble in alcohol.
Like neodicumarin, it is a 4-hydroxycoumarin derivative but contains one 4-hydroxycoumarin group.
The mechanism of action also refers to antagonists of vitamin K. It violates the synthesis of prothrombin, proconvertin, factors IX and X.
Fepromaron has a long anticoagulant effect. It has a cumulative effect. It is more active than neodicumarin, and is prescribed in smaller doses.
Indications for use, contraindications and precautions are the same as for neodikumarin.
Prescribe the drug inside. Doses are selected individually. The initial dose is 0.5 mg per 1 kg of the patient’s body weight, i.e. 30 - 50 mg (0.03 - 0.05 g).
Maintenance doses are 0.01 - 0.005 g (10 - 5 mg) per day or every other day; depending on the content of prothrombin in the blood, the maintenance dose can be increased or decreased.
Release form: tablets of 0.01 g in a package of 20 pieces.
Storage: List A. In the dark place.