Medication Description: Probucol (Probucol)
PROBUCOL (Probucol). 4, 4 '- (Isopropylidenditio) -bis (2, 6-di-tert-butylphenol).
Synonyms: Lipomal, Bifenabid, Fenbutol, Lesterol, Lipomal, Lorelcol, Luisosterol, Lursele, Sinlestal, Superlipid.
Probucol inhibits cholesterol biosynthesis, in addition, reduces the absorption of cholesterol from food. Little effect on blood concentrations of triglycerides and VLDL.
The drug is slowly absorbed when taken orally. Excreted mainly in the bile and feces, to a small extent with the urine.
Applied with hypercholesterolemia, diseases of the coronary vessels, accompanied by hyperlipoproteinemia.
Assign adults inside 0.25 g, 2 times a day (during breakfast and dinner). The therapeutic effect usually develops during the first 2 months.
The drug is usually well tolerated, but dyspeptic symptoms are possible. It does not cause gallstones formation; It enhances the excretion of bile acids with feces.
Probukol is contraindicated in pregnancy and lactation.
Product form: tablets of 0.25 g (250 mg) in a package of 50 and 60 pieces.