Description of the medicine: Probucol (Probucol)
PROVOCOL (Probucol). 4, 4 '- (Isopropylidendithio) bis (2, 6-di-tert-butylphenol).
Synonyms: Lipomal, Bifenabid, Fenbutol, Lesterol, Lipomal, Lorelcol, Luisosterol, Lursele, Sinlestal, Superlipid.
Probucol inhibits the biosynthesis of cholesterol, in addition, reduces the absorption of cholesterol from food. Little effect on the concentration of triglycerides and VLDL in the blood.
The drug is slowly absorbed when taken orally. It is excreted mainly with bile and feces, to a small extent with urine.
Used for hypercholesterolemia, diseases of the coronary vessels, accompanied by hyperlipoproteinemia.
Assign to adults inside 0.25 g 2 times a day (during breakfast and dinner). The therapeutic effect usually develops during the first 2 months.
The drug is usually well tolerated, but dyspeptic symptoms are possible. Probucol does not cause the formation of gallstones; it enhances the secretion of bile acids with feces.
Probucol is contraindicated in pregnancy and lactation.
Release form: tablets of 0.25 g (250 mg) in a package of 50 and 60 pieces.