Medication Description: Hydrolysin (Hydrolysin)
The product obtained by acid hydrolysis of blood proteins of cattle with the addition of glucose.
Transparent brown liquid with a specific odor; pH 6, 4 - 7, 4. Contains a set of amino acids, including essential amino acids, including tryptophan. 100 ml of the drug should contain at least 15 mg of tryptophan. The content of total nitrogen is 0.7 - 0.8%; of this amount, the nitrogen of free amino acids is 40–60%. The preparation contains 1, 6 - 2, 2% glucose.
Hydrolysin is well absorbed and can serve as a complete product for parenteral protein nutrition. It also has a detoxification effect.
Hydrolysin solution, like other solutions for parenteral nutrition, is widely used for diseases accompanied by protein deficiency, and, if necessary, enhanced protein nutrition (with hypoproteinemia and depletion of the body, including gastrointestinal diseases with impaired protein absorption, with intestinal obstruction, intoxication, burn disease, sluggish granulating wounds, radiation sickness, etc.), as well as inability to feed through the mouth (after operations on the esophagus, stomach, etc.). Solutions for parenteral nutrition are widely used to improve metabolic and reparative processes in the postoperative period.
The hydrolysin solution can be administered intravenously or via a probe into the stomach or into the small intestine.
The introduction of the hydrolysin solution should be made dropwise (with all methods of administration), starting from 20 drops per minute, with good tolerance, the number of drops can be increased to 40 - 60 per minute. With a quicker introduction, there may be a sensation of heat, flushing of the face, difficulty in breathing.
The daily dose is 1, 5 - 2, 0 l. The solution is heated to body temperature before administration.
With the introduction of a vein, you must carefully monitor the reaction of the patient.
The drug (like other similar hydrolysates) should not cause anaphylactogenic and pyrogenic reactions. If side reactions (chills, fever, weakness) develop, they are usually caused by poor quality of the applied series of the drug or insufficient treatment of the system for transfusion.
Contraindications to the use of the hydrolysin solution are acute hemodynamic disturbances (traumatic shock, operative, burn, massive blood loss, etc.), cardiac decompensation, cerebral hemorrhage, acute and subacute hepatic and renal failure, thromboembolic diseases and conditions that are impossible drip infusions of the drug (sharp arousal, etc.).
Product: in hermetically sealed vials of 450 ml.
Storage: at a temperature of + 4 to + 20 'C.