Description of the medicine: Hydrolysin (Hydrolysin)
Product obtained by acid hydrolysis of cattle blood proteins with the addition of glucose.
Transparent brown liquid with a specific odor; pH 6, 4 - 7, 4. It contains a set of amino acids, including essential amino acids, including tryptophan. 100 ml of the drug should contain at least 15 mg of tryptophan. The total nitrogen content is 0.7 - 0.8%; of this amount, nitrogen of free amino acids is 40-60%. The preparation contains 1, 6 - 2, 2% glucose.
Hydrolysin is well absorbed and can serve as a complete product for parenteral protein nutrition. It also has a detoxifying effect.
Hydrolysin solution, like other solutions for parenteral nutrition, is widely used for diseases accompanied by protein deficiency, and if necessary, enhanced protein nutrition (with hypoproteinemia and exhaustion, including gastrointestinal diseases with impaired absorption of proteins, with intestinal obstruction, intoxication, burn disease, sluggishly granulating wounds, radiation sickness, etc.), as well as the inability to eat through the mouth (after operations on the esophagus, stomach, etc.). Solutions for parenteral nutrition are widely used in order to improve metabolic and reparative processes in the postoperative period.
The hydrolysin solution can be administered intravenously or via a tube into the stomach or small intestine.
The introduction of the hydrolysin solution should be carried out dropwise (with all methods of administration), starting from 20 drops per minute, with good tolerance, the number of drops can be increased up to 40-60 per minute. With a faster introduction, a sensation of heat, hyperemia of the face, difficulty in breathing are possible.
The daily dose is 1, 5 - 2, 0 liters. The solution is heated to a body temperature before administration.
When injected into a vein, it is necessary to carefully monitor the patient's reaction.
The drug (like other similar hydrolysates) should not cause anaphylactogenic and pyrogenic reactions. If adverse reactions develop (chills, fever, weakness), then they are usually due to the poor quality of the used series of the drug or insufficient treatment of the system for transfusion.
Contraindications to the use of hydrolysin solution are acute hemodynamic disorders (traumatic shock, surgical shock, burn, massive blood loss, etc.), decompensation of cardiac activity, cerebral hemorrhage, acute and subacute hepatic and renal failure, thromboembolic diseases and conditions in which it is impossible to conduct long-term drip infusions of the drug (sharp excitement, etc.).
Release form: in hermetically closed bottles of 450 ml.
Storage: at a temperature of + 4 to + 20 'C.