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Cardiotonic drugs

Cardiotonic drugs are widely used to treat cardiac non-
sufficiency. For a long time, almost the only means, at-
changing for this purpose were cardiac glycosides. With an acute heart
adrenaline was sometimes used, and later became
change more modern adrenomimetic drugs (see KIsadria, Dopamine,
Dobutamine). Recently, new cardiotonic
zidny and nonadrenergic pririda (see. Amrinon), however the main
diotonics used to treat chronic heart failure -
However, cardiac glycosides continue to remain.
It should be borne in mind that recently the tactics of drug therapy
heart failure has become more perfect. Along with drugs,
stimulating myocardial contractile activity, are widely used -
means that reduce the load on the myocardium and facilitate the work of the heart,
reducing the energy expenditure of the heart muscle and improving such
way its function is not by stimulation, but by its more economical activity
nost. Such means of complex therapy are primarily
spherical vasodilators (see), reducing pre- and afterload by
myocardium by decreasing peripheral vascular resistance and
expansion of the peripheral vascular bed, as well as K diuretic media
actions that reduce the load on the myocardium, exerting a hypovolemic effect
effect, i.e., reducing the volume of circulating blood plasma.
To a certain extent, they imply cardiotonic properties,
having a general positive effect on the metabolic processes of
nism, including myocardial metabolism (see. Anabolic hormones, Riboxinum
and etc.).