Acetylsalicylic acid (aspirin)
- on pharmacological action is close to sodium salicylate. For anti-inflammatory properties somewhat inferior to him. Apply inside with neuralgia, migraine, febrile diseases 0.25-1 g 3-4 times a day. In acute rheumatism, rheumatic endo and myocarditis, the dose of adults is 6-4 g per day. Children are prescribed as an antipyretic and analgesic agent in a dose of 0.01-0.3 g per dose, depending on age. Aspirin less frequently than sodium salicylate causes side effects associated with impaired function of the nervous system, but relatively often there are complications of the stomach. Long-term, especially without medical supervision, the use of aspirin can cause dyspeptic symptoms and even stomach bleeding. This so-called ulcerogenic effect is due to the effect on the pituitary gland and adrenal cortex, on blood clotting factors and direct irritation of the gastric mucosa. Therefore, you should take salicylates only after a meal, pill carefully crushed and drink plenty of liquid (preferably milk). To reduce the irritating effect, alkaline mineral waters and sodium bicarbonate (soda) solutions are used after acetylsalicylic acid, although they contribute to a more rapid release of salicylates from the body. Contraindications for receiving salicylates - peptic ulcer, venous congestion, blood clotting disorders. With long-term use of salicylates should consider the possibility of anemia and systematically conduct blood tests and check for blood in the feces. When using acetylsalicylic acid, allergic reactions can be observed: bronchospasm, angioedema, skin reactions. The following finished dosage forms (tablets) containing acetylsalicylic acid are produced.