(sulfonamides, nitrofurans, antibiotics). Antimicrobials are called chemotherapeutic
agents that selectively act on the activity of certain bacteria. Modern chemotherapy arose at the end of the last century with the development of microbiology, when the role of microorganisms in the occurrence of diseases was established, and the progress of chemistry made it possible to synthesize substances with antibacterial properties.
For the successful use of chemotherapeutic agents, it is necessary to strictly adhere to the following rules:
1. A bacteriological diagnosis must be accurately established, ie it should be known what microorganisms caused the disease. However, with a difficulty in the bacteriological diagnosis, one should not hesitate with the start of treatment. In such cases, drugs with a wide spectrum of antimicrobial action are used.
2. Treatment should be started as early as possible. It must be borne in mind that microorganisms multiply very quickly, and the greater their number, the more difficult the fight against them.
3. Chemotherapeutic drugs must be prescribed in maximum doses in order to energetically affect microorganisms, preventing them from adapting, ie get used to new conditions.
4. Treatment with chemotherapeutic agents must be carried out within the prescribed period, without interrupting it even with improvement.
5. If possible, carry out combined treatment, ie apply not one, but different means, with different mechanisms of action on microorganisms. This prevents the appearance of forms of microorganisms resistant to individual drugs.
6. Timely re-treatment when it is indicated.
7. In the treatment of infectious diseases, strive not only to destroy pathogenic bacteria, but also take measures to eliminate pathological changes in the body caused by infection.
8. Conduct a general strengthening treatment to enhance the body's resistance.
Unfortunately, many chemotherapeutic agents can cause side effects. The most commonly observed: a) impaired renal activity, b) allergic reactions, c) poisoning (toxicosis) caused by the breakdown products of microorganisms, d) disorders by suppressing chemotherapeutic agents of the normal bacterial and fungal flora of the intestine.
Infectious Diseases for All
Diseases of the ear, nose and throat
Modern research methods