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Antimicrobial agents


(sulfonamides, nitrofurans, antibiotics). Antimicrobial agents are called chemotherapy.
means selectively acting on the activity of certain bacteria. Modern chemotherapy began at the end of the last century with the development of microbiology, when the role of microorganisms in the occurrence of diseases was established, and the progress of chemistry provided the possibility of the synthesis of substances with antibacterial properties.
For the successful use of chemotherapeutic agents, you must strictly adhere to the following rules:
1. Bacteriological diagnosis must be accurately established, i.e. it must be known which microorganisms caused the disease. However, if the bacteriological diagnosis is difficult, it is impossible to delay the start of treatment. In such cases, use drugs with a broad spectrum of antimicrobial action.
2. Treatment should begin as early as possible. It must be borne in mind that microorganisms multiply very quickly, and the greater their number, the more difficult it is to fight them.
3. Chemotherapeutic drugs should be prescribed in maximum doses in order to energetically affect microorganisms, preventing them from adapting, i.e. get used to the new conditions.
4. Treatment with chemotherapeutic agents must be carried out within the prescribed period, without interrupting it even with improvement.
5. If possible, conduct a combined treatment, i.e. apply not one, but different means, with different mechanisms of action on microorganisms. This prevents the emergence of resistant to individual drugs forms of microorganisms.
6. Timely re-treatment when it is indicated.
7. In the treatment of infectious diseases, strive not only to eliminate pathogenic bacteria, but also take steps to eliminate the pathological changes in the body caused by infection.
8. To carry out general strengthening treatment to increase the body resistance.
Unfortunately, many chemotherapeutic agents can cause side effects. The most frequently observed are: a) impaired kidney function, b) allergic reactions, c) poisoning (toxicosis) caused by decomposition products of microorganisms, d) disorders from the suppression of normal bacterial and fungal intestinal flora by chemotherapeutic agents.






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